作者Ice98 (又寂寞又美好)
看板NEMS
標題[分享] 讓PDMS變成親水性的方法
時間Tue May 27 20:46:09 2008
最近做了一點功課, 在此與大家分享
[PDMS的親疏水性]
PDMS has repeating uints of –OSi(CH3)2- groups. This chemical structure
leads to a hydrophobic surface.
Exposing this surface to an air or oxygen plasma introduces silanol (Si-OH)
groups, destroys methyl groups (Si-CH3), and makes the surface hydrophilic.
PDMS that has been treated with plasma can be kept hydrophilic indefinitely
by keeping the surfaces in contact with water or polar organic solvents.
Otherwise, If the surface is left in contact with air, surface rearrangements
occur that bring new hydrophobic groups to the surface to lower the surface
free energy.
Ref:
J. N. Lee, C. Park and G. M. Whitesides, “Solvent compatibility of
poly(dimethylsiloxane)-based microfluidic devices”, Anal. Chem., Vol. 75,
2003, pp. 6544-6554
[Method 1] Extraction
1. Immerse in an extremely soluble solvent, diisopropylamine (DIPA), to extract
the soluble components from cross-linked PDMS.
2. Immerse in ethyl acetate (1 day) and acetone (2 days) and then dry in a 90°C
oven for 2 days.
3. Oxygen plasma treatment.
Ref:
J. N. Lee, C. Park and G. M. Whitesides, “Solvent compatibility of
poly(dimethylsiloxane)-based microfluidic devices”, Anal. Chem., Vol. 75,
2003, pp. 6544-6554
[Method 2] Sog-Gel Modification
1. PDMS were solvated in tetraethyl orthosilicate (TEOS), causing them to
expand. (TEOS is potentially hazardous, and appropriate precautions should be
taken when using it)
2. Placed in an aqueous solution containing 2.8% ethylamine.
3. Rinse with ultrapure water.
4. Place in an oven at 95°C for 1 h to form nanometer-sized SiO2 particles
within the cross-linked PDMS polymer.
Ref:
G. T. Roman et al., “Sol-gel modified poly(dimethylsiloxane) microfluidic
devices with high electroosmotic mobilities and hydrophilic channel
wallcharacteristics”, Anal. Chem., Vol. 77, 2005, pp. 1414-1422
[Method 3] Plasma-Induced Grafting
1. Bath with diethyl ether and acetone.
2. Rinse with detergent solution and DI water.
3. Argon and hydrogen plasma treatment.
4. Immerse into acrylonitrile solution for 4 h.
5. Rinse with acetone, ethanol, detergent solution and DI water.
6. Dry at 100°C for 1 h.
Ref:
Q. He et al., “Preparation of hydrophilic poly(dimethylsiloxane) stamps by
plasma-induced grafting”, Langmuir, Vol. 19, 2003, pp. 6982-6986
[Method 4] Modify with HEMA
1. Oxygen plasma treatment.
2. Spin coat 2-hytdroxy ethyl methacrylate (HEMA).
3. Oxygen plasma treatment.
Ref:
D. S. Bodas and C. Khan-Malek, “Fabrication of long-term hydrophilic
surfaces of poly(dimetheyl sioxane) using 2-hydroxy ethyl methacrylate”,
Sensors and Actuators B, Vol. 12, 2007, pp. 719-723
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◆ From: 140.112.14.214
1F：推 eagleman:推 常用的方法 可用來bonding PDMS 05/27 20:52
2F：→ Ice98:請問樓上的 哪種比較好用ㄚ =.=a 05/27 21:42
3F：推 eagleman:我們是打氧電漿 05/27 21:43
4F：→ Ice98:只打氧氣電漿好像撐不到一天... Orz 05/27 21:50
5F：推 oactioner:氧電將打完要泡水裡面 才能稱比較多天 05/27 21:51
6F：→ oactioner:pdms泡鹽酸也有親水性效果 但好像不會超過1星期 05/27 21:53
7F：→ pinlittle:ps一下..如果要養細胞,可以先coat一層ECM molecule.. 05/27 22:02
8F：推 largesperm:打 ICP 6 秒 ... 再把兩片 PDMS 合在一起就行了 05/27 22:56
9F：→ largesperm:放太久還是會變回疏水性的 05/27 22:57
10F：→ pinlittle:我忽然想到...我們為何不換種材料...幹嘛一定什麼都要 05/27 23:12
11F：→ pinlittle:PDMS...然後再那邊想辦法改質搞的要死... 05/27 23:12
12F：→ pinlittle:我承認我有點瘋...但我們要是找到另一種不錯的材料 05/27 23:13
13F：→ pinlittle:不也是一篇好文章~~~ 05/27 23:13
14F：推 oactioner:NOA63好像可以取代 有PAPER 05/27 23:19
15F：→ oactioner:Simple Route to Hydrophilic Microfluidic Chip 05/27 23:20
16F：→ oactioner:Fabrication Using an Ultraviolet (UV)-Cured Polymer 05/27 23:20
17F：→ yanzichiro:之前我們買了一台電暈的儀器 05/30 00:38
18F：→ yanzichiro:只用儀器在其表面上掃過幾秒 放入烤箱 05/30 00:39
19F：→ yanzichiro:可以完全接合 那台儀器是可以PORTABLE的 挺方便 05/30 00:40
20F：推 Jinuse:樓上說的是corona discharging 好用但是不適用在導電物體 05/30 02:05
21F：→ Jinuse:我們之前有拿PDMS去試看看 但是因為下面有導電層會讓他短路 05/30 02:06
22F：推 MicroOptics:我的疑問是親水性和疏水性對PDMS的最大影響為何 06/14 20:31
23F：推 peter33:如果PDMS後續製程需與玻璃等表面具親水性質的材料結合 07/16 11:01
24F：→ peter33:把PDMS用O2 plasma使其也具親水性會比較適合 07/16 11:03
25F：推 roguematt:請問電暈的儀器可以讓PDMS與PMMA接合嗎?接合後PDMS裡有 09/09 14:49
26F：→ roguematt:微流道，裡面通水，通水後會讓接合失效嗎? 09/09 14:51