※ 引述《wgs (我需要超級機械可魯)》之銘言： : 請問各位神人 : CH3 : ∣ CH3OH : CH3C——CH2 -----------------> ? : ＼╱ ∣ H﹢ ---------------- : O ∣ : ∣ : ∣ CH3ONa : ∣----------------> ? : CH3OH ---------------- : 請問這兩者不同的酸是如何開環加成的 : 我有考慮到二級碳一級碳的問題 可是想不出所以然 : 有高手知道嗎 As treating this epoxide with proton in MeOH, protonation occurs to generate the epoxide-proton cation, which could be regard as the equivalent of alpha-hydroxy tertiary carbon cation... thus the methanol addition takes place on the tertiary carbon to form the alpha-hydroxyl ether. but to deal the epoxide with sodium methoxide, no elimination will happen because non of the protons of epoxide would be trapped by methoxide anion. Based on this, no reaction will undergo but nucleophilic attack. the less steric hindered carbon attacked by methoxide resulted in ring opening to form another kind of alpha-hydroxyl ether. -- 在人的一生當中，誰沒有一些...醒不了的夢；揮不去的痛． 我想，只要待人以誠，愛人以真，從來沒有刻意去傷害誰． 只希望能做到............不負人，不負我！ --

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