作者huachi (开始领取医用台语)
看板NTUH-INTERN
标题[小儿] Intern seminar题目
时间Mon Jul 14 22:30:45 2008
礼扬
Which statement is NOT true for CSD (cortical spreading depression)?
(A) Marked, enduring depression of the spontaneous electrical activity
that spreads out slowly in all directions.
(B) NMDA receptors account for CSD more than AMPA and kainate receptors.
(C) There is a consensus(共识) that CSD accounts for epilepsy initiation.
(D) There is a consensus(共识) that CSD accounts for migraine aura.
(E) CSD may causes migrainous pain by irritating nociceptors in pia and
dura mater.
答案:(C)
虽然偏头痛和癫痫同样都是大脑电活性过高造成,但癫痫是皮质的高度同步放电
(hypersynchronous activity)引起,而偏头痛目前的共识是由CSD造成。
广元
下列关於inflammatory bowel disease治疗方法之叙述,请选出错误者:
(a)对於严重程度是mild to moderate的病人,先给予口服的5-ASA compound如
sulfasalazine, mesalazine等做induction therapy。而比较奇怪的是mesalazine
在Crohn's disease虽然常用於induction,但没有evidence证明有效。
(b)在只侵犯distal part的ulcerative colitis病人,可采用rectally给药
(mesalazie enema或suppository)。
(c)急性期发作压下来以後,仍需持续用药以达到maintenance of remission。
Azathioprine与6-MP因其onset比较慢,是maintenance常用的药。
(d)Steroid类的药物如prednisolone、budesonide等等,不论是oral或IV给药,
为了避免副作用的产生,是其他immunosuppresants都没有效之後最後一线
的选择。
ans: (d)
峻玮
IBD:
Which of the following factor is least associated with inflammatory bowel
disease?
1. infectious microbes
2. genetic susceptibility
3. dysregulated immune system
4. height
Ans. 4
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