多少可以参考一下吧~ 课程名称︰分析化学丁 课程性质︰必修 课程教师︰何国荣 开课系所︰医技系、药学系 考试时间︰2006/4/24 10:20~12:10 试题 : Analytical Chemistry (120 points) 1. Briefly answer the following questions. 30% (a) sampling (b) sample preparation (c) qualitative analysis (d) amphiprotic species (e) variance (f) false negative (g) limit of quatitation (h) quality assessment (i) buffer solution (j) isoelectric focusing 2. Draw the following three titration curves on the same diagram. 12% (a) titration of a strong acid with a strong base (b) titration of a weak acid which has the same concentration as the strong acid in (a) (c) titration the same strong acid as in (a) but is more diluted 3. Derive the exact equation for a buffer solution. 5% 4. In a weak acid solution, please show that the dissociation is less than 5% if Ka/C ﹤2.5*10^-3. 5. Explain the fact that the elimination of the contribution of H2O dose not significantly simplify the calculation of pH of an amphiprotic solution. 5% 6. Calculate the [H+] of a 10^-8 M KOH solution. 5% 7. (a) State a method and the steps for the detection of systematic error. (b) State the reason that one can not make a conclusion that there is no systematic error. 8% 8. A 25 mL class A pipet delivers 25.00 ±0.03mL, calculate the uncertainty if you use (a) the same pipet (b) different pipet to deliver 100 mL solution. 6% 9. List the two assumptions in the concentration of a calibration curve. 6% 10. If accuracy is defined as how close an average value to the true value. State the reason that accuracy can be improved by increasing the number of measurement on the same sample. 5% 11. You prerared a 0.250 M NH3 solution by diluting 8.45(±0.04) mL of 28.0(±0.5) wt%NH3 [density = 0.899(±0.003) g/mL] up to 500.0 (±0.2) mL. Find the uncertainty in 0.250 M. Consider the molecular mass of NH3, 17.031 g/mol, to have negligiable uncertainty. 5% 12. Convert [H+] = 1.0*10^-5 to a pH value. 4% 13. State the reason that, in general, five points are needed to establishing a calibration curve. 5% 14. State the reason of estimating detection limit before establishing a detection limit. 5% 15. State the advantages of using internal standard in the establishing a calibration curve. 5% 16. State (a) purpose (b) requirements in the validation of an analytical method in pharmaceutical chemistry. 3+5% 注：超过98分以98分计。 --

※ 发信站: 批踢踢实业坊(ptt.cc) ◆ From: 140.112.250.39