※ 引述《kuwawa (库瓦瓦)》之铭言： : ※ 引述《ashin1069 (谢金燕我可以)》之铭言： : : 我是说真的，这也是药师跟我说的 : : (以下是很多人应该知道的) : : 练肌肉需要 (分泌) 睾固酮与肝醣 : : 所以练肌肉到一个程度的时候 : : 会有可能导致睾固酮分泌不足 : : 所以在运动之前可以去药局买银杏 (或是银杏膜衣锭) : : 运动之前吃，可以促进多增加分泌睾固酮 : : 且可以让血液末梢流动顺畅 : : 大家可以参考看看 (或是可以再询问药师细节) : 借这篇文章内容问一下, : 依照ashin1069大大所说的, 练肌肉会消耗睾固酮, : 那是否可减缓雄性秃 : 我是渐进性雄性秃, 已经努力挣扎近十年. : 之前有吃波斯卡来压抑睾固酮, 但近半年来为了练muscle而停药 找到一篇网路文章, 节录相关重点. 大意就是, 肌肉需要的是原始的睾固酮(Testosterone), 而Proscar或柔沛等药物是 抑制 将睾固酮 转化成二氢睾固酮( DHT)的 酵素, 并非抑制睾固酮的分泌, 所以对 肌肉不会有直接的影响 .然而(我恨然而), DHT对神经系统,以及肝有影响, 所以 服用Proscar的某些人仍然会觉得运动表现下降不少. (ps, 我不太确定 "and greater recoverability" 的含义, 难道是指肌肉的recovera- bility? 但这样解释不就又对肌肉有直接影响了?) Testosterone Is The Active Androgen In Muscle Skeletal muscle is unique from other androgen dependent tissues in the body. It actually contains little or no 5-AR, so little or no DHT is actually formed in the muscle. In addition to this, any DHT that is formed, or that is already present in the blood and travels to the muscle, is quickly deactivated by an enzyme called 3alpha-hydroxysteroid reductase (3a-HSD). So at least as far as muscle is concerned, testosterone is the primary active androgen. This is not to say that administering exogenous DHT is not without any anabolic effect. It actually does have some anabolic activity in the muscle, albeit significantly weaker than that of an equal amount of testosterone. This is due to its quick breakdown by 3a-HSD into the weak metabolite 5alpha-androstan-3a, 17b-diol. If this enzyme were somehow blocked, it is likely that DHT would exhibit very potent anabolic effects on muscle. It is important to understand that even though testosterone is the active androgen in muscle, and DHT exhibits relatively little direct anabolic effects on muscle in men, DHT is still very important for the full performance enhancement effects from testosterone. What I specifically mean here are the effects of DHT on the central nervous system that lead to increased neurological efficiency (strength), and increased resistance to psychological and physical stress—not to mention optimal sexual function and libido. I have heard several anecdotal reports of individuals who have stacked testosterone with Proscar (a 5-AR inhibitor) and have noticed significantly reduced performance enhancement effects. What's going on here? We know it couldn't be due to the inhibition of the direct anabolic activity of testosterone on muscle anabolism. Most likely it is due to the reduction of androgenic effects in other parts of the body that contribute to the ergogenic effects. Specifically the CNS, which is stimulated by androgens to increase neural output leading to greater strength and greater recoverability. Another possibility is a reduction in the production of androgen dependent liver growth factors (such as IGF-1), since DHT is an important androgen in the liver. --

※ 发信站: 批踢踢实业坊(ptt.cc) ◆ From: 24.6.100.140