P.27 第九题 我之前解考古题的时候，不小心多解了两题 这是我查到的资料,我不知道选(E)会不会比较合适 1. http://ndt.oxfordjournals.org/cgi/content/abstract/13/5/1183 for example, it is known that LDL exhibits heterogeneity, with small dense LDL III particles being more atherogenic. 意思就是LDL有分几种种类，LDL I 是比较大的， LDL III就是所谓的small density LDL，也是目前公认最具有atherogenic的 2. Galeano, N. F., M. Al-Haideri, F. Keyserman, S. C. Rumsey, and R. J. Deckelbaum. J. Lipid Res. 1998. We hypothesize that small dense LDL might be more atherogenic than normal size LDL due to decreased hepatic clearance by the LDL receptor, and enhanced anchoring to LDL receptor-independent binding sites in extrahepatic tissues (e.g., the arterial wall), a process mediated, in part, by cell surface proteoglycans. Small dense low density lipoprotein has increased affinity for LDL receptor-independent cell surface binding sites: a potential mechanism for increased atherogenicity. sorry...排版的很乱>.< --

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