作者wuuuu (正忠好吃)
看板CMU_M50
标题[课程] 医学研究方法论文第五周 abstract
时间Wed Apr 1 23:45:31 2009
老师说这篇很简单，
下次上课会点人上去讲
所以各位同学务必看一下吧!
Study objective:
We sought a marker to differentiate tuberculous pleural effusions from
nontuberculous pleural effusions, which otherwise can be difficult.
Patients:
We studied 55 patients with pleural effusions, 20 (36%) with tuberculous
pleuritis and 35 (64%) with a nontuberculous etiology.
Measurement and results:
Pleural fluid levels of adenosine deaminase, interferon (INF)-γ,
interleukin (IL)-12p40, IL-18, immunosuppressive acidic protein, and soluble
IL-2 receptors were measured and were subjected to receiver operating
characteristic analysis. INF-γhad the greatest sensitivity and specificity
for tuberculous pleuritis among the six biological markers studied.
Conclusion:
The determination of INF-γlevels in pleural fluid is the most
informative in the diagnosis of tuberculous effusion.
Key words:
cytokine; diagnosis; pleural fluid; tuberculous pleuritis
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