作者shuehan (shuehua)
站内Biotech
标题[期刊] 比较广泛的生物议题
时间Tue Apr 9 11:52:51 2013
我们在这里讨论比较广泛的议题,所以需要参考的文献也比较多一些
最新的生物科技发展是很令人关注的,譬如细胞层次的研究。
这篇研究探讨心肌梗塞的治疗方式,不同的心肌梗塞病患的恢复情况,与体内或
体坏的细胞的关联Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy
The POSEIDON Randomized TrialAMA. 2012;308(22):2369-2379. doi:10.1001/jama.
2012.25321
http://jama.jamanetwork.com/article.aspx?articleid=1388970
这篇相关研究聚焦在慢性缺血性心脏衰竭,跟上一篇一样是进行细胞层次的
讨论与研究,值得看一下。
Rationale and design of the first randomized, double-blind, placebo-controlled trial of intramyocardial injection of autologous bone-marrow derived Mesenchymal Stromal Cells in chronic ischemic Heart Failure (MSC-HF
Trial) American Heart Journal
Volume 164, Issue 3 , Pages 285-291, September 2012
http://tinyurl.com/cytaglu
这篇研究与儿童的骨质发育不全有关,探讨为什麽细胞的作用可以改善儿童的
骨质发育不全与可能的机制
Otsuru, et al.
Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms
Blood 2012 120:1933-1941
http://tinyurl.com/cen44n7
这篇研究主要探讨多重系统退化症的应对方法,本文提到一个新的方法,同样跟细胞
层次的治疗有关,值得一读。
A randomized trial of mesenchymal stem cells in multiple system atrophy
Annals of Neurology
Volume 72, Issue 1, pages 32–40, July 2012
http://tinyurl.com/czulc3n
这篇研究讨论,发生慢性肝病的病患,肝脏细胞纤维化是主要问题,如何减缓或改善
这样的症状,这篇论文是临床试验的结果。
Human umbilical cord mesenchymal stem cells improve liver function and
ascites in decompensated liver cirrhosis patients
Issue
Journal of Gastroenterology and Hepatology
Special Issue: 6th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis, 20-21 October 2011, Fukuoka, Japan
Volume 27, Issue Supplement s2, pages 112–120, March 2012
http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1746.2011.07024.x/abstract
椎间盘退化造成病患很大的痛苦,这篇文章研究改善症状的方法,经过分析,可改善
病人的下背痛问题。
Transplantation. 2011 Oct 15;92(7):822-8. doi: 10.1097/TP.0b013e3182298a15.
Intervertebral disc repair by autologous mesenchymal bone marrow cells:
a pilot study.
http://tinyurl.com/czsukxb
这篇文章研究糖尿病的治疗,针对第型糖尿病提出新的治疗方法,并以临床实验方式,
证明新的方式是安全的。
Front Med. 2011 Mar;5(1):94-100. doi: 10.1007/s11684-011-0116-z. Epub 2011 Mar 17.
Transplantation of placenta-derived mesenchymal stem cells in type 2 diabet
es: a pilot study.
http://link.springer.com/article/10.1007%2Fs11684-011-0116-z
这篇文章讨论韧带受伤的治疗方式,经过临床试验,认为进行细胞层次的治疗是未来
可能可以应用的方式。
Equine Vet J. 2012 Jan;44(1):25-32. doi: 10.1111/j.2042-3306.2011.00363.x. Epub 2011 May 26.
Implantation of bone marrow-derived mesenchymal stem cells demonstrates improved outcome in horses with overstrain injury of the superficial dig
ital flexor tendon.
http://onlinelibrary.wiley.com/doi/10.1111/j.2042-3306.2011.00363.x/abstract
膝盖的退化性关节炎困扰众多病患,这篇文章初步提供四个人的试验资料,采用新的治
疗方式,并提出相关内容。
Int J Rheum Dis. 2011 May;14(2):211-5. doi: 10.1111/j.1756-185X.2011.01599.x. Epub 2011 Mar 4.
Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of
four patients.
http://tinyurl.com/bowpsm9
以上讯息,与网友们分享,并欢迎来信与我讨论
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※ 编辑: shuehan 来自: 113.196.92.66 (04/10 09:49)
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