[申覆] 醫學六　31 答案: B.懷孕前服用葉酸及多種維生素,懷孕後接受高層次超音波檢查 這答案好像已經把etiology設定為:Folic acid deficiency 其它的etiology也包括了:Genetic factors -->那麼D也應該是答案之一 Genetic factors — A genetic factor is suggested by the observations that NTDs have a high concordance rate in monozygotic twins, are more frequent among siblings, and are more common in females compared to males [9]. In addition, there is a high prevalence of karyotypic abnormalities among fetuses with NTDs, especially in the presence of other congenital anomalies. For example, a large study evaluating the frequency of chromosomal abnormalities in pregnancies with fetal NTDs found these abnormalities in 6.5 percent of affected cases (4/167 fetuses with an isolated NTD and 9/33 fetuses with a NTD and associated anomalies) [10]. A second series reported a similar rate (7 percent) of chromosomal abnormalities in fetuses with NTDs [11]. Trisomy 18 was the most common aneuploidy in both series. These data support the use of fetal karyotyping as an aid in diagnostic evaluation and recurrence risk counseling. 資料來源: Uptodate.com - Anencephaly and encephalocele 建議B,D皆給分 覆議的請推文 謝謝 --

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