※ [本文轉錄自 b97902xxx 看板 #1ERaUszV ] 作者: GraceOhyes (happy ending) 看板: b97902xxx 標題: [徵人] Bioinformatics Intern/Distance Intern 時間: Tue Sep 13 01:56:03 2011 Project Description: Fall 2011 Bioinformatics Intern/distance internship. At this time, we have two openings for research intern/distance intern at the Biomedical Cybernetics Laboratory with faculty affiliated with Harvard and MIT. Our projects involve machine learning and network analysis method development, and application to bring bottom-up data-driven (e.g. Bayesian network learning) and top-down knowledge-driven approaches (ontologies) together and abstract out key information/underlying relationships. These projects involve work with a laboratory affiliated with the Children’s Hospital Informatics Program at the Harvard/MIT Division of Health Sciences and Technology. There are two opportunities that require strong programming skills (medicine/molecular biology, CS, engineering, math, and/or physics background a plus). For one opportunity, a strong background in medicine/molecular biology, genetics, and evolution would be a plus. For the other opportunity, a background in probability, network theory, linear algebra, machine learning, and/or signal processing would be a plus. One research project involves work on biomolecular and knowledge networks. Specifically, we are looking at learning new knowledge (applicable to diseases) from large, interconnected biological datasets. This project involves developing inference framework from biomedical literature through cutting edge learning and inference techniques over Bayesian networks. The other opportunity involves working with genome-scale data to capture the complex pattern of dependency among causal genetic and environmental variants for several diseases and behaviors such as lung cancer, pancreatic cancer, alcoholism, and nicotine dependence. The goal of this project is to integrate the small to moderate effect size of many causal variants underlying complex traits to obtain a comprehensive picture of the traits. We will construct prognostic models able to predict the risk of developing of the traits. Some features of this particular opportunity include: - Potential for a high-impact publication by the end of the opportunity (previous students alums have won national awards and have been accepted to top graduate/medical programs including Harvard MD/PhD). - Networking at Harvard/MIT community via lab meetings, journal club, seminars, etc. - A self-contained project that can be done within a semester or two- but also has room for expansion for the ambitious student. - Flexible work hours - Independence (can be a plus or minus- i.e. student must be highly motivated and put in the time to be successful). - Flexible start/end dates Please note that this opportunity may be either for-credit, experience, or potentially funding. - Can work from abroad and/or come to US for summers, term, etc. In the past, this led to a master thesis for the international student. - Please apply asap as the 2 positions are being filled on rolling basis. Contact: Please send a CV to Aaron Merlob at ([email protected]) if you are interested. http://www.mit.edu/~gil/ --

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