1. According to the trial of TOBY study group for discussing the hypothermic therapy effect on neurodevelopmental outcomes in newborn infants with asphyxial encephalopathy, which of the following newborn baby could be most possibly enrolled to this trial of TOBY? (A) male, GA 37wks, 1 day of age, Apgar: 4 at 10mins after birth, seizure pattern on aEEG, hypotonia, abnormal reflexes (B) female, GA 38wks, 3 hours of age, Apgar: 9 at 10mins after birth, normal aEEG (c) male, GA 37wks, 4 hours of age, acidosis (arterial pH < 7.0) within 60 mins after birth, lethargy, absent sucking reflex, abnormal background activity on aEEG (d) male, 3 hours of age, Apgar: 5 at 10mins after birth, with high arched palate, epicanthic fold, muscle hypotonia, single palmar fold, abnormal background activity on aEEG (e) female, GA 34wks, 2 hours of age, Apgar: 4 at 10mins after birth, abnormal reflexes, clinical seizures 2. According to the result of TOBY trial of moderate hypothermia for 72 hrs in newborn infants with asphyxial encephalopathy, which outcome(s) of the following choices has(have) significant difference between cooled and uncooled group? (1) Primary outcome: Combined death & severe neurodevelopmental disability (2) Secondary outcome: survival without neurologic abnormalities (3) Secondary outcome: Hearing loss not corrected by aids (4) Secondary outcome: GMFCS score shows no abnormality (5) Secondary outcome: Cerebral palsy (6) Secondary outcome: Head circumference at follow0-up > 2SD below the mean (A) 1+2+3+4+5 (B) 1 only (C) 3+5+6 (D) 2+4+5 (E) non of the above 如果出越多加越多的話...那來幾題送分題好了...答案就不用給了吧? 哈哈 3. According to the content of discussion during the intern seminar, about the topic of hypothermia to treat perinatal asphyxial encephalopathy, Which of the following is correct? (A) The paper presenters have mentioned the different cooling therapies of different trials, including cooling of the whole body, of the head, and also cooling of the buttocks (B) According to Dr. Chen, we are going to have a machine for hypothermia therapy too in NTUH, this machine which we're going to buy is invented and manufactored by Korean people (C) Ri Wang has presented the highest speed but also during the longest time among all 3 interns (D) For the paper published by the Chinese doctors, their machine for cooling the heads of newborn infants was manufactored by an professional American medical equipment company (E) Perinatal asphyxial encephalopathy is also known as HIE (hypoxemic ischemic encephalopathy) Ans: 1. (C) 2. (D) --

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