5/8 influenza virus and pneumococcus的題目~ Ans: (D) According to the study of Lethal Synergism between Influenza Virus and Streptococcus pneumoniae: Characterization of a Mouse Model and the Role of Platelet-Activating on Infectious Diseases Society of America in 2002, which of the following is wrong? A. Influenza virus infection primes for development of lethal pneumococcal pneumonia and bacteremia in a dose dependent fashion B. Seven days between infectious agents produces the greatest effect; C. More extensive and severe pathologic findings are seen than in classic lobar pneumonia; D. Preceding pneumococcal infection worsens survival from influenza E. Pneumococcus can cause pneumonia and bacteremia by pathways independent of the platelet activating factor receptor Ans: (C) About the interaction between influenza virus and pneumococcus, which of the following statement is wrong? A. Much of the morbidity and mortality from pandemic disease from influenza virus stemmed from bacterial complications. B. The combined effect of the bacterial and viral NAs at the site of infection is an important mechanism in synergism between the two organisms. C. The expression of PAF-R is upregulated by inflammatory cytokines and is necessary for the induction of secondary pneumonia D. Treatment of influenza with NA inhibitors (oseltamivir) can lower respiratory tract complications, antibiotic use, and hospitalizations could be prevented. --

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