1. Which one of the following is incorrect about PTLD (Post-Transplantation Lymphoproliferative Disorder)? (A) It is often associated with EBV. (B) Clinical presentations of PTLD include FUO, mononucleosis-like syndrome, and abdominal mass lesion. (C) It occurring after the first year is usually T cell and NK cell in origin, and its prognosis is the best. (D) Diagnostic methods include viral loading, flow cytometry, and analysis of immunoglobulin gene rearrangement. Answer：(C) 第一年內多為 CD 20+ B cell origin, 預後稍好一點點; 一年之後多為 T cell and NK cell，預後很差 2. Which one of the descriptions concerning solid-organ transplantation is incorrect? (A) It is more difficult to recognize infection in transplant recipients. (B) Successful transplantation has been achieved in HIV-infected patients. (C) Catheter infection is one of the common causes of infections during early post-transplantation period. (D) Live vaccines is definitely a good choice of prevention of post-transplantation infections. Answer: (D) 3. Which one of the following statements concerning risk assessment in children with ALL is incorrect? (A)Goal of risk assessment is to prevent relapse by using intensive treatment. (B)Age is a strong prognostic factor; the younger is always the batter. (C)Increasing leukocyte count confers a poorer outcome, espicially in B-cell precursor disease. (D)Molecular and flow-cytometric method increase the sensitivity in assessing response to treatment. Answer: (B) Age is a strong prognostic factor, usually the young the batter, whereas children younger than 1 y/o have lower 5-year-survival rate. 4. Which of following hypotheses is incorrect about clustering of childhood leukaemia cases? (A)Kinlen’s population-mixing hypothesis (B)Greaves’ delayed-infection hypothesis (C)Radiation-related hypothesis (D)all of above Answer: (C) 5. An important element of PCOS is insulin resistance. Insulin impedes ovulation by what? (A) affect follicular development (B) increase intraovarian androgen level (C) alter gonadotropin secretion (D) all of above Answer: (D) 6. Which of following is used for the treatment of the polycystic ovary syndrome? (A) Combination of estrogen and progestin (B) Antiandrogens (C) Antiestrogen (D) Biguanide (E) All of the above Answer: (E) 7. Which of the following is the symptoms a patient with polycyctic ovary syndrome (PCOS) may have? (A) Infertility (B) Hirtuism (C) Dysmenorrhea (D) Impaired glucose tolerance (E) All of the above are the symptoms a patient with PCOS may have Answer: (E) --

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