課程名稱︰普通生物學乙上 課程性質︰必修 課程教師︰陳俊宏 開課學院：醫學院 開課系所︰醫學系 考試日期（年月日）︰2007／12／06 考試時限（分鐘）：110min 是否需發放獎勵金：是 （如未明確表示，則不予發放） The Midterm Examination of General Zoology (Part ⅡB) Ⅰ. Multiple-choice Questions (20 points) 1. Which of the following statements about the difference in the way B cells and cytotoxic T cells respond to invaders is correct? Ⅰ. B cells kill viruses directly; cytotoxic T cells kill virus-infected cells. Ⅱ. B cells accomplish humoral immunity; cytotoxic T cells accomplish cell- mediated immunity. Ⅲ. B cells secret antibodies against a virus; cytotoxic T cells kill virus- infected cells. Ⅳ. B cells activity is T_H-dependent; cytotoxic T cells activity is T_H- independent. A. Ⅰ and Ⅱ. B. Ⅱ and Ⅲ. C. Ⅲ and Ⅳ. D. Ⅰ and Ⅳ. 2. What are antigens? A. Macromolecules embedded in B-cell membranes. B. Foreign molecules trigger the generation of antibodies. C. Proteins are released during an inflammatory response. D. Molecules consist of two light and two heavy peptide chains. 3. One kind of gap junctions joined the cardiac muscle cells is A. tendon. B. sarcomere. C. intercalated disc. D. Haversian system. 4. The activation of receptor tyrosine kinases is always characterized by A. IP3 formation. B. GTP hydrolysis. C. a phosphorylation cascade. D. dimerization and autophosphorylation. 5. Matrix of CNT include all of the following except A. plasma of blood. B. hydroxyapatite of bone. C. actin and myosin of muscle. D. chondroitin sulfate of cartilage. 6. Which of the following is the best example of positive feedback? A. gastrin secretion. B. trypsin activation. C. secretin regulation. D. cholecystokinin secretion. 7. What will be the major concern for an individual with type A blood who receives a transfusion of type B blood? A. the antibodies in the serum of the recipient. B. the anti-A antibodies produced by the donor. C. the antigen on the type A blood of the recipient. D. the antibodies in both the donor's and recipient's serum. 8. Which of the following characteristics of blood best explains its classification as connective tissue? A. Its cells can move from place to place. B. It is found within all the organs of the body. C. It contains more than one type of blood cells. D. Its cells are widely dispersed and surrounded by a fluid. 9. What is the function of the parietal cells in your stomach. A. HCl secretion. B. HCO3- secretion. C. mucous secretion. D. pepsinogen secretion. 10. Which of the following is a correct statement about pepsin? A. It is produced by the pancreas. B. It splits maltose into monosaccharrides. C. It is activeated by the action of HCl on pepsinogen. D. It helps to maintain the acidic condition in stomach. 11. Which of the following is the best example of an effector's response in negative feedback? A. An increase in body temperature is resulting from fever. B. An increase in body temperature is resulting from exercise. C. An increase in body temperature is resulting from shivering. D. An increase in body temperature is resulting from exposure to the sun. 12. A patient reports severe symptoms of sneezing, runny nose, and rearing eyes after a picnic at spring season. A reasonable initial treatment would involve the use of A. interferon. B. antiserum. C. penicillin. D. antihistamine. 13. Which of the following would be inhibited by a drug that specifically block the addition of phosphate groups to proteins? A. GTPase activity. B. adenynyl cyclase activity. C. receptor tyrosine kinase activity. D. G-protein-linked receptor signaling. 14. A person iwth AIDS will not be suffered from which of the following diseases? A. cancer. B. hepatitis. C. influenza. D. rheumatoid arthritis. 15. In which of the following situations will helper T cells be activated? A. when a cytotoxic T cell releases interleukin Ⅰ. B. when an antigen is displayed by a dentritic cell. C. when an antigen is bound on a B cell surface. D. when an antigen presenting cell release interleukin Ⅱ. 16. Which of the following statements about bioenergetics is true? A. Endotherms are warmed by metabolic heat. B. An animal's metabolic rate is rare to change. C. SMR is best measured just after a meal of an ectotherm. D. BMR can be determined only at a specific temperature. 17. Which of the following minerals is INCORRECTLY associated with its use in animals? A. phosphorous - ingredient of nucleic acid. B. magnesium - important in nerve function. C. iron - construction and maintenance of bone. D. sodium - cofactor in enzymes that split ATP. 18. Which of the following is directly involved in the activation and functioning of cytotoxic T cells? A. interleukins. B. class Ⅰ MHC molecules. C. antigen presenting cells. D. CD8 molecules on T cell surface. 19. Which of the following statements is INCORRECT? A. Cyclic AMP binds to calmodulin. B. Diacylglycerol is an activator for PKC. C. Phospholipase C catalyzes the formation of IP3. D. Kinases are enzymes that phosphorylate other molecules. 20. When a person lack ▁▁▁ may have a higher than normal chance of developing cancer. A. helper T cells. B. macrophages. C. cytotoxic T cells. D. natural killer cells. Ⅱ. Fill-in (15 points): 1. Cells fused from myeloma and spleen cells are called ____________________, which might produce monoclonal antibodies. 2. ____________________ including heat-shock protein in bacteria, fungi, plant cells and animal cells can be synthesized in minutes to maintain the integrity of other protein that would be denatured by severe heat. 3. The three stages of cell signaling are signal reception, __________________, and cellular response. 4. The patient with severe hypersensitivities should carry syringes containing ____________________. 5. ____________________ (lupus) is an autoimmune disease, which autoantibodies are against all sorts of self molecules including histone and DNA. 6. ____________________ can be use to describe that many animals can adjust to a new range of environmental temperature over a period of many days or weeks. 7. A major thermoregulatory adaption in mammals and birds is __________________ by hair, feathers, or fat layer. Terrestrial mammals raise their fur to form ____________________, which can trap still air. 8. ____________________ signaling such as growth factors travel only short distances to serve as local regulator. 9. ____________________ hold bones together at joints. 10. Animals digest food by enzymatic ___________________, and energy-containing molecules are absorbed by the cells, which are used to generate ATP by the catabolic processes such as cellular respiration or ____________________. 11. If the MHC of the bone marrow transplant donor and the recipient do not match well, the transplanted bone marrow cells will cause ________________. 12. Viagra, a cGMP-specific ____________________ inhibitor, causes dilation of blood vessels, which allows increased blood flow to the penis. 13. ____________________ can simultaneously bind several relay proteins to facilitate a specific enzyme cascade. Ⅲ. Question (15 points): As you know, a Rh- mother is hard to keep her second Rh+ baby. 1. If she insists to keep the baby, she has to take immuno-suppressor drug during the process of second time pregnant. Please use the example to describe "clonal selection," and "immunological memory." 2. If you were her clinical doctor, what kind of putative immuno-suppressor drug will be used to treat your patient? Please explain the pharmacological mechanism of the drug you might use. --

※ 發信站: 批踢踢實業坊(ptt.cc) ◆ From: 140.112.7.214 ※ 編輯: shokanshorin 來自: 140.112.7.214 (07/22 21:22) ↑已修正。今天打起來手很殘... ↑其實我算是來騙p幣的(艸) 因為這其實是同一次期中考的 只是兩個老師一個出動物學一個出植物學 覺得不方便的話就直接延用2nd-1,2nd-2就可以了 到時候發獎勵金的時候被當成兩份考題的話就算爽到吧>.< (實際上考卷也的確是兩份，並沒有被訂在一起) ※ 編輯: shokanshorin 來自: 140.112.241.199 (07/22 23:21)