課程名稱︰普通生物學乙上 課程性質︰必修 課程教師︰陳俊宏 開課學院：醫學院 開課系所︰醫學系 考試日期（年月日）︰2009／10／26 考試時限（分鐘）：110min 是否需發放獎勵金：是 （如未明確表示，則不予發放） Ⅰ. Choose the optimal alternative that feets the statement or answers the question. One point for each question. 1. By what technique biologists can visualize cytoskeleton? A. freeze-etching and SEM. B. heavy metal staining and TEM C. immunolabeling and confocal microscopy. D. ultracentrifugation. E. living call and Phase microscopy. 2. Which of the following compounds require the presence of the nuclear pores to move between the cytoplasm and the interior of the nucleus? A. ribosomal RNA. B. proteins synthesized in the cytoplasm that are part of ribosomes. C. messenger RNA. D. A and B only. E. A, B, and C. 3. The major component of nuclear lamina is A. rubisco B. microtubule. C. intermediate filament. D. microfilament. E. collagen. 4. Which of the following is not considered part of the endomembrane system? A. nuclear envelope. B. peroxisome. C. Golgi body. D. plasma membrane. E. SER. 5. Of the following, what do both mitochondria and chloroplasts have in common? A. DNA is present. B. ATP is produced. C. Ribosomes are present. D. B and C only. E. A, B, and C are correct. 6. Motor proteins provide for molecular motion in cells by interacting with what types of cellular structures? A. sites of energy production in cellular respiration. B. cytoskeletons. C. cellulose fibers in the cell wall. D. membrane proteins. E. ribosomes. 7. The extracellular matrix is thought to participate in the regulation of animal cell behavior by communicating information from the outside to the inside of the cell via A. gap junctions. B. DNA and RNA. C. integrins. D. the nucleus. E. plasmodesmata. 8. Ions can travel directly from the cytoplasm of one plant cell to the cytoplasm of an adjacent cell through A. desmosomes. B. gap junctions. C. tight junctions. D. plasmodesmata. E. intermediate filaments. 9. Which of the following types of molecules are the major structural components of the cell memebrane? A. phospholipids and proteins. B. glycoproteins and cholesterol. C. proteins adn cellulose. D. nucleic acids and proteins. E. phospholipids and cellulose. 10. What is one of the functions of cholesterol in animal cell membranes? A. facilitates transport of ions. B. phosphorylates ADP. C. maintains membrane fluidity. D. speeds diffusion. E. stores energy. 11. Which of the following is a characteristic feature of a carrier protein in a plasma membrane? A. It exhibits a specificity for a particular type of molecule. B. It works against diffusion. C. It requires the expenditure of cellular energy to function. D. It is a peripheral membrane protein. E. It has few, if any, hydrophobic amino acids. 12. The selective permeability of biological membranes is dependent on which of the following? A. the type of transport proteins that are present in the membrane. B. the lipid bilayer being permeable to primarily small, nonpolar molecules C. the types of carbohydrates on the surface of the membrane. D. A and B only E. A, B, and C. 13. Glucose diffuses slowly through artificial phospholipid bilayers. The cells lining the small intestine, however, rapidly move large quantities of glucose from the glucose-rich food into their glucose-poor cytoplasm. Using this information, which transport mechanism is most probably functioning in the intestinal cells? A. active transport pumps. B. exocytosis. C. facilitated diffusion. D. phagocytosis. E. simple diffusion. 14. An organism with a cell wall would have the most difficulty doing which process? A. acitve transport. B. exocytosis. C. diffusion. D. osmosis. E. phagocytosis. 15. ATP is often an allosteric inhibitor of key enzymes in catabolic pathways. Which of the following statements is INCONSISTENT with the role of ATP? A. The binding of ATP to allosteric sites on enzymes of the catabolic pathway decreases the production of ATP by the pathway. B. Increasing availability of ATP increases the energy available to drive endergonic reaction steps. C. When ATP levels are high in the cell, it is an indication that energy supply from catabolicreactions exceeds evergy demand by anabolic reactions. D. When ATP levels are low in the cell, there is no inhibition of the catabolic pathway and ATP production is at a maximum. E. ATP couples energy production in catabolic pathways to energy demand in anabolic pathways. 16. Which of the following is true of enzymes? A. Enzymes may require a nonprotein cofactor or ion for catalysis to take places. B. Enzyme function is influenced by physical and chemical environmental factors such as pH and temperature. C. Enzyme function is reduced if the three-dimensional structure or conformation of an enzyme is altered. D. Enzymes increase the rate of chemical reaction by lowering activation energy barriers. E. All of the above are true of enzymes. 17. Which of the following statements concerning the metabolic degradation of glucose (C6H12O6) to carbon dioxide (CO2) and water is true? A. The breakdown of glucose to carbon dioxide and water is exergonic. B. The breakdown of glucose to carbon dioxide and water has a free energy change of -686 kCal/mol. C. The breakdown of glucose to carbon dixoide and water involves oxidation- reduction or redox reactions. D. only A and B are correct. E. All of the above statements are correct.(means except D) 18. Oxidative phosphorylation, TCA cycle and lactic fermentation take place in the subcellular locations, respectively, __________. A. inner mitochondrial membrane, cytosol, and cytosol. B. inner mitochondrial membrane, mitochondrial matrix, and cytosol. C. inner mitochondrial membrane, cytosol, and mitochondrial matrix. D. inner mitochondrial membrane, mitochondrial matrix, peroxisome. E. plasma membrane, mitochondrial matrix, peroxisome. 19. 　Ｘ　 is the direct substrate of citric acid cycle, and the acceptor of X ￣￣￣ is ▁▁▁; how many CO2 will be released from one run of the cycle? A. pyruvate; malic acid; 3. B. pyruvate; Oxaloacetate; 3. C. acetyl-CoA; malate; 2. D. acetyl-CoA; Oxaloacetate; 2. E. acetyl-CoA; citrate; 2. 20. How many reduced dinucleotides would be produced with three turns of the citric acid cycle? A. 3 FADH2 and 6 NADH. B. 3 FADH2 and 9 NADH. C. 3 FADH2 and 12 NADH. D. 3 FAD and 6 NAD+. E. 3 FAD+ and 9 NAD+. --

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