清華大學、交通大學 統 計 學 研 究 所 專 題 演 講 題 目: Alternative Transition Equations of Genotypic Frequencies under Random Mating 主講人: 高振宏博士 (中央研究院 統計科學研究所) 時 間: 96年5月25日（星期五）10：40 - 11：30 （上午10：20-10：40茶會於統計所821室舉行） 地 點: 清大綜合三館837室 Abstract After Mendel's garden pea experiment in 1886, the characterization of genotypic distribution of a population from generation to generation under random mating has been a historically important and interesting issue in statistical genetics. Under random mating, Hardy and Weinberg (1908) demonstrated that the allelic frequencies and genotypic frequencies for one gene are constant in the absence of disturbing forces. Jennings (1917) and Robbins (1918) formulated the transition equations of gametic frequencies to characterize the genotypic frequencies for two genes. Geiringer (1944) extended their works by proposing transition equations of gametic frequencies for multiple genes to complete the issue of characterizing the genotypic distribution under random mating. These transition equations have been well documented in the books by Falconer (1960, 1981, 1989), Wright (1968), Crow and Kimura (1970), Falconer and Mackay (1996) and Weir (1996), and widely applied to the general genetic and biological studies. We propose alternative transition equations of gametic frequencies for multiple genes. We found that the proposed and Geiringer’s transition equations are theoretically identical, but may have different behavior in practice. The proposed and Geiringer’s transition equations are compared genetically and numerically. This talk is based on the joint work with Miao-Hui Zeng. 敬請公佈 歡迎參加 --

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