Adolescent Brains Biologically Wired to Engage in Risky Behavior, Study Finds ScienceDaily (June 3, 2010) — There are biological motivations behind the stereotypically poor decisions and risky behavior associated with adolescence, new research from a University of Texas at Austin psychologist reveals. Previous studies have found that teenagers tend to be more sensitive to rewards than either children or adults. Now, Russell Poldrack and fellow researchers have taken the first major step in identifying which brain systems cause adolescents to have these urges and what implications these biological differences may hold for rash adolescent behavior. "Our results raise the hypothesis that these risky behaviors, such as experimenting with drugs or having unsafe sex, are actually driven by over activity in the mesolimbic dopamine system, a system which appears to be the final pathway to all addictions, in the adolescent brain," Poldrack said. Poldrack, a professor in the departments of Psychology and Neurobiology, directs the university's Imaging Research Center, where researchers use functional Magnetic Resonance Imaging technology (fMRI) to study brain activity. He collaborated on the study with researchers at UCLA, including Jessica Cohen and Robert Asarnow. In the study, participants ranging in age from eight to 30 performed a learning task in which they categorized an abstract image into one of two categories and were given feedback displaying the correct response. To ensure motivation, they were given monetary rewards for each correct answer. What the researchers were most interested in, however, was how each participant's brain responded to "reward prediction error" (or the difference between an expected outcome of an action and the actual outcome) as they learned to categorize the images. "Learning seems to rely on prediction error because if the world is exactly as you expected it to be, there is nothing new to learn. " Poldrack said. Previous research has shown that the dopamine system in the brain is directly responsive to prediction errors. Researchers measured so-called positive prediction error signals in the participants' brains as the participants discovered the results of their answers and the size of their rewards. Teenagers showed the highest spikes in these prediction error signals, which likely means they had the largest dopamine response. Dopamine is known to be important for the motivation to seek rewards. It follows, then, that the greater prediction error signals in the adolescent brain could result in increased motivation to acquire more positive outcomes, and therefore greater risk-taking. Poldrack is confident future studies will further explore the biological reasons for stereotypical adolescent behavior. As to whether any study can absolve teens of blame for their antics, he said, "That's a question for the philosophers." -- 原始網址： http://www.sciencedaily.com/releases/2010/06/100603132458.htm 大意就是，為什麼青少年需要冒險、尋求刺激？例如透過藥癮、濫交來滿足自己。 這篇提供了一個看法，青少年的身體本來就是尋求刺激。而這個行為和我們的邊緣系統 limbic system或稱多巴胺的路徑有關。 研究者利用prediction error的task來觀看，8~30歲這些受試者的reward機制。 並發現青少年會有最強的prediction error的反應。 不過最後一段蠻有趣的，被問到是否可以赦免這些青少年的責任時，Poldrack表示 『這是一個哲學問題』XDDDD --

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