Clinical correlation 1 Questions: 1.How and why, based on what serum biochemical exams, does Graves’disease diagnosed? 蔡承恩 2.Please point out the clinical signs the patient have and explain the physio-pathological mechanism 謝博堯 3.What is the mechanism by which high levels of iodine inhibit thyroid production? 吳銘展 4.How does propylthiouracil(PTU) inhibit thyroid synthesis? 王明方 5.What effect does pregnancy have on the free thyroid hormone level? 李柔慧 Clinical correlation 8 Questions 1.According to steroid hormone synthesis, what is the role/function of 11β -hydroxylase? Whatis the mechanisms and influences if the enzyme was deficient? 張維剛 2.Why the plasma ACTH and testosterone were increased in Anne’s case? 郭昭成 3.Why did Anne have increased size of clitoris and hyperpigmented genitalia? 劉臻 4.Did Anne have metabolic acidosis or alkalosis? Why? 林晉賢 5.How does the treatment: hydrocortisone and captopril work for Anne’s symptoms? 曾淑期 6.What would be happening in the process of development if Anne did not found to be 11β-hydroxylase deficient and had no treatments at all? 江品儀 ●書面收稿、PPT收稿：天使的右手 ●期末考命題：cfuryu ◎交稿時間：2010.6.2 晚上10點以前 {不准脫稿} ◎討論時間：2010.6.9 下午3~5點 醫學大樓601 THX --

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