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請醫、中二同學於課前先找以下相關資料參考 參考資料 High-altitude illness References: 1. Mark D. Harris,et al., High-Altitude Medicine, Am Fam Physician. 1998 Apr 15; 57(8):1907-14, 1924-6. 2. Marco Maggiorini, High altitude-induced pulmonary oedema, Cardiovascular Research xx (2006) xxx–xxx (in press) 3. Buddha Basnyat, David R Murdoch, High-altitude illness, 2003; Lancet 361: 1967–74. 4. A. Roberto Frisancho, Functional Adaptation to High Altitude Hypoxia , 1975, Science 187: 313-319 5. Lionel Dumont, Chahe Mardirosoff, Martin R Tramer, 2000; Efficacy and harm of pharmacological prevention of acute mountain sickness: quantitative systematic review, BMJ 321:267–72 Hemoglobin References: 1. We learn in Junior science that the blood going from the lungs is a different colour to the blood returning after the red blood cells have dropped off their load of oxygen. But what is going on at molecular level, where the action really happens? Max Perutz won the Nobel Prize for Chemistry in 1962 for studies in the structure of globular proteins, together with John Kendrew. Perutz's part was for solving the structure of haemoglobin and elucidating the mechanism of its action. You can read Max Perutz's biography on the Nobel e-musuem site at www.nobel.se /chemistry/laureates/1962/perutz-bio.html. 2. From Nobel Lectures, Chemistry 1942-1962, Elsevier Publishing Company, Amsterdam, 1964 3. Lehninger Principles of Biochemistry, 4th ed. (2005) David L. Nelson and Michael M. Cox. (Chapter 5, p162) 4. Textbook of Biochemistry with Clinical Correlation, 6th ed. (2006) Thomas M. Devlin, John Wiley & Sons, Inc. (Chapter 9, p338) 5. Biochemistry, 3rd ed. (2005) P. C. Campe and R. A. Harvey, Lippincott’s Illustrated Reviews(Chapter 3) 6. Biochemistry, 6th ed. (2007) Jeremy M. Berg et al. John L. Tymoczko, Lubert Stryer(Chapter 7) --



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