作者luciferwing (瘋子真多)
看板Anti-Cancer
標題[問題] 乳房切片報告請教
時間Sat Aug 24 15:40:47 2024
從健保快譯通得到的乳房切片報告
看起來確定是乳癌了
想請教是否看得出哪種類型的乳癌/幾期以及是否擴散？
感謝各位
Breast, right, 10 o'clock position/3 cm from nipple, core needle biopsy, ductal carcinoma in situ with invasions (invasive carcinomas and mucinous carcinoma)The specimen submitted consists of five tissue fragments measuring up to 1.7 x 0.1 x 0.1 cm in size, fixed in formalin. Grossly, they are gray and cordlike. All for section.Histologic type of right breast (10'/3) tumor: Mixed invasive carcinomas and mucinous carcinoma, some foci Histologic grade: Grade 1 (provisional in biopsy specimen) Tubule and
gland formation: < 10% (score: 3) Nuclear pleomorphism: Moderate (score: 1) Mitotic count: < 7/10 HPF (score: 1) Total score: 5 Histologic feature: Extensive spreading of ductal carcinoma in situ with some foci of invasions presenting infiltrative nests, strands and cords set in the sclerotic and desmoplastic stroma; presence of mucinous carcinoma Ductal carcinoma in situ (DCIS): Present Microcalcifications: Present in DCIS Peritumoral lymphovascular invasion: Not present in this small biopsy Perineural
invasion: Not present in this small biopsy Immunohistochemical stains (for invasions): p63: Loss of myoepithelial rimming Estrogen receptor (ER): < 1% Progesterone receptor (PR): < 1% HER2/neu protein: Positive, score 3+ Ki67 proliferation index: 5%
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1F：推 aka79019: 切片報告沒辦法看出是第幾期，腫瘤大小跟是否擴散才是判 08/24 20:27
2F：→ aka79019: 斷期別的依據，但這個要靠影像檢查才能知道 08/24 20:27
3F：→ luciferwing: 好的了解 感謝回覆 08/25 09:24
4F：推 Euglena: 分化度很低的乳癌，或是預後很好的粘液性乳癌；分期從切 08/25 19:50
5F：→ Euglena: 片看不出來。 08/25 19:50
6F：推 fafagood: 看起來是黏液性的導管癌DCIS，一般來說屬於預後較好的種 08/26 00:48
7F：→ fafagood: 類，但仍需要進一步檢查，需要注意的是ER/PR受體陰性而H 08/26 00:48
8F：→ fafagood: ER2陽性反應，需跟主治醫師討論是否需要使用標靶藥物 08/26 00:48
9F：→ luciferwing: 好的～感謝樓上兩位的回覆 08/26 16:28
10F：推 eric15234: 這就是Her2 陽性的類型吧 09/09 16:23