作者hoe1101 (摸摸)
看板pharmacist
标题[申覆] 治疗 18
时间Tue Aug 3 14:48:57 2010
[完整题目与选项]
18.高血压患者有下列何种疾病不适合以hydrochlorothiazide来治疗?
(A)骨质疏松
(B)糖尿病
(C)中风
(D)痛风
[考选部公布之原答案]
(D)
[应修正之答案]
(B)(D)
[理由来源之文献课本与页数]
(1)Human Phamacology 4th edition p.178左边的图(名称为Clinical Problem)
Thiazides里有提及metabolic changes (hyperglycemia, hyperlipidemia, insulin
resistance)
(2)Goodman & Gilman's The Phamacological Basis of Therapeutics(11th ed.)
p.765
Thiazide diuretics also decrease glucose tolerance, and latent diabetes
mellitus may be unmasked during therapy.
以及同页
In addition to contributing to hyperglycemia, thiazide-induced hypokalemia
compromises the antihypertensive effect (Wilcox, 1999) and cardiovascular
protection (Franse et al., 2000) afforded by thiazeds in patients with
hypertention.
药理学的参考用书拿来申覆药物治疗学应该OK吧?
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◆ From: 114.32.155.232
※ 编辑: hoe1101 来自: 114.32.155.232 (08/03 15:15)
1F:推 dunkyou:想请教一下,因为thaizide会造成高血钙,对於骨质疏松病患 08/03 17:43
2F:→ dunkyou:是否也会有影响@@ 08/03 17:44
3F:推 pharmawind:To楼上: 对於骨质疏松的高血压病人 thiazide是首选药 08/03 18:14
4F:→ naomi0215:这题申覆应该稳过的(影响BS与UA) 08/03 18:19
5F:推 dunkyou:我忘了这题才刚翻过,感谢大大以正视听= = 08/03 18:25
※ 编辑: hoe1101 来自: 114.32.155.232 (08/04 07:44)
※ 编辑: hoe1101 来自: 114.32.155.232 (08/04 08:50)
※ 编辑: hoe1101 来自: 114.32.155.232 (08/04 08:51)