作者mercury99986 (汪汪)
看板medstudent
标题Re: [申覆] 医学(六) 54
时间Wed Aug 4 11:16:28 2010
Novak 13e
5a-Reductase Deficiency 5a-Reductase deficiency should also be considered as a
cause of amenorrhea ( 21).
Patients with this disorder are genotypically XY,
frequently experience virilization at puberty, have testes (because of
functioning Y chromosomes), and have no mullerian structures due to functioning
mullerian-inhibiting factor (MIF). 5a-Reductase converts testosterone to its
more potent form, dihydrotestosterone........Normal male differentiation of
the urogenital sinus and external genitalia do not occur, because
dihydrotestosterone is required for this development. However, normal internal
male genitalia derived from the Wolffian ducts are present because this
development requires only testosterone.
由此可知病患为正常46 XY染色体,为
男性假性阴阳人(male pseudohermaphroditism)
所以选项中四个叙述均描述此病患为
女性,与医学上的判定有Y染色体即为
男性的事实不符合,因此选项描述错误造成考生误解,建议应一律送分
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