作者oesh (非人类 )
看板gay
标题[心情] 稍微找了一下关於药的资讯
时间Wed May 26 12:15:28 2010
英文翻错的话 麻烦大家更正一下
因为我不是这个领域的
所以有些东西我不太了解
1.精神分裂症
Limited data indicate that drug abuse is already prevalent before
the manifestation of psychosis, consistent with the possibility
that drug abuse might be associated with increased risk for schizophrenia.
The prevalence of self-reported drug abuse in adolescents later hospitalized
for schizophrenia was 12.4%, compared with 5.9% prevalence of drug abuse in
adolescents not later hospitalized; adjusted RR = 2.016, 95% confidence
interval: 1.309–3.104 (Wesier et al. 2003).
.
药物滥用 可能提升精神分裂症的风险，
精神分裂去就医的青少年中 => 12.4%承认药物滥用
没有精神分裂的青少年中 => 5.9%承认药物滥用
（Wesier et al. 2003）
2.ecstasy成瘾性
Animal evidence suggests that MDMA may be a less potent reinforcer
than other drugs, but that it does have dependence potential.
This suggests that (a) ecstasy dependence might be less likely than
dependence upon other drugs; and (b) factors related to the behavioural
and psychological aspects of reward and dependence may make a relatively
greater contribution for ecstasy than for other drugs, where physically
centred (and better understood) features of dependence may be more salient
(Degenhardt et al. 2010).
动物研究显示，ecstasy(MDDA)比起其他药物有较低的强度，
但是依然会有可能会造成成瘾性，Ecstasy的依赖情形可能低於其他药物，
且在心理性的依赖会比其在生理上的作用多来得多（Degenhardt et al. 2010）。
3.神经损伤
Our data suggest that ecstasy use, particularly in high doses,
is associated with greater parietal activation during working memory
performance. An altered activation pattern might appear before changes
in cognitive performance become apparent and, hence, may reflect an early
stage of neuronal injury from the neurotoxic drug ecstasy (Daumann et al. 2004).
使用摇头丸，特别是在高剂量的时候，会影响的激活顶叶的记忆区域，
激活模式的改变可能出现在认知变得明显之前，
这可能反映了从ecstasy而来的早期神经损伤（Daumann et al. 2004）.。
参考文献(依姓氏字母排列)
1.Daumann J, Fischermann T, Heekeren K, Thron A, Gouzoulis-Mayfrank E. 2004.
Neural mechanisms of working memory in ecstasy (MDMA) users who continue or
discontinue ecstasy and amphetamine use: Evidence from an 18-month
longitudinal functional magnetic resonance imaging study. Biological
Psychiatry 56( 5): 349-55.
2.Degenhardt L, Bruno R, Topp L. 2010. Is ecstasy a drug of dependence?.
Drug and Alcohol Dependence 107(1): 1-10
3.Weiser M, Reichenberg A, Rabinowitz J, Kaplan Z, Caspi A, Yasvizky R,
Mordechai M, Knobler HY, Nahon D, Davidson M. 2003. Self-reported drug
abuse in male adolescents with behavioral disturbances, and follow-up for
future schizophrenia. Biological Psychiatry 54(6): 655-60.
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◆ From: 218.173.244.226
1F：推 honkwun:good! 05/26 12:16
2F：→ autosun:关於菸酒对身体造成伤害的研究也很多喔 05/26 12:18
3F：推 sigon:认真文 =) 不过 需要注意的是: 在国外文献中 通常在讲 05/26 12:20
4F：→ sigon:drug abuse 指涉得非常广 而派对药物只占其中一小块 05/26 12:21
5F：→ sigon:更多的时候是讲吗啡类的药物 通常最常指涉的是海洛因 05/26 12:22
6F：→ sigon:我没有去查原文 不过可以的话 是否也可以请你把他们定义的 05/26 12:23
7F：→ sigon:"drug"也一并贴出来呢?? 05/26 12:24
8F：推 genica:substance abuse 05/26 12:36
9F：推 stts:此篇专业 05/26 13:11
10F：推 vicdaniel:推 05/26 13:21
11F：→ uka123ily:其实心理的依赖性 谈恋爱也不会很低 05/26 13:40
12F：推 potatofat:不要互相谩骂 这样讨论很好阿 05/26 13:50
13F：→ potatofat:看到专业文很开心 05/26 13:51
※ 编辑: oesh 来自: 218.173.244.226 (05/26 13:56)
14F：推 sigon:抱歉抱歉 您对於精神分裂症那篇论文的翻译还是有点问题 05/26 14:15
15F：→ sigon:该文主要的依变项是是否"有住院"(然後才细分诊断) 05/26 14:16
16F：→ sigon:因此，应该是翻做"未住院"的人之中有5.9%有自陈药物滥用史 05/26 14:17
17F：→ sigon:未住院 并不代表没有精神分裂症的诊断喔 =) 05/26 14:18
18F：→ sigon:如果要完整得翻译 或许"之後未因精神分裂症住院的人"中... 05/26 14:20
19F：→ sigon:这样会比较准确 =) 05/26 14:20