※ 引述《phiby (超可爱猫)》之铭言： : ※ 引述《chihlingchen (.........)》之铭言： : : 我吃3颗 中午1颗 晚上2颗 : : 平常不觉得吃这个药对自己的情绪有什麽改善 : : 前几天晚上去看电影 结果忘了晚上该吃的2颗 : : 隔天开始就一直昏昏沉沉想睡觉 一直狂睡 : : 什麽事都不想做 真糟糕 也不想吃东西 : : 一开始吃时食慾很差 体重直直落 : : 习惯这个药之後就好了点 : : 但是那天忘了吃之後 身体变的怪怪的 : : 什麽都不想 不想吃 不想动 又变瘦了 : : 我实在不想再瘦下去 3字头让人觉得瘦得恶心>< : : --------------------------------------------- : : 初次po文 今天才发现除了prozac之外 还有这个版쨊: 我大约两周前有碰到一个吞服28天Efexor剂量要自杀的病人 : 当天在急诊做完简单的处理後就收到我们病房来了 : 至於over dose 的 sign 几乎没有文献记载 : 当天早上入院 下午2PM病人开始 sizure, 而且意识欠清 : 眼神无打对焦 呈惊獗状, 而且当天病人 sizure 两次 : 尿也尿不出来 所以on上导尿管..... : 我po这篇的目的是 大家在用药上要小心, 医生是专业的 : 想减药可以跟医生商量 不要自己减药或调药 If you take too many Efexor-XR capsules you may: * feel sleepy; * have an increased heart rate; * have a seizure (fits); * have breathing difficulties; * become unconscious; * have dilated pupils. 以上出自http://health.ninemsn.com.au/MEDICATIONS/ ====================================== OVERDOSAGE Human Experience There were 14 reports of acute overdose with Effexor (venlafaxine hydrochloride), either alone or in combination with other drugs and/or alcohol, among the patients included in the premarketing evaluation. The majority of the reports involved ingestions in which the total dose of Effexor taken was estimated to be no more than several-fold higher than the usual therapeutic dose. The 3 patients who took the highest doses were estimated to have ingested approximately 6.75 g, 2.75 g, and 2.5 g. The resultant peak plasma levels of venlafaxine for the latter 2 patients were 6.24 and 2.35 μg/mL, respectively, and the peak plasma levels of O-desmethylvenlafaxine were 3.37 and 1.30 μg/mL, respectively. Plasma venlafaxine levels were not obtained for the patient who ingested 6.75 g of venlafaxine. All 14 patients recovered without sequelae. Most patients reported no symptoms. Among the remaining patients, somnolence was the most commonly reported symptom. The patient who ingested 2.75 g of venlafaxine was observed to have 2 generalized convulsions and a prolongation of QTc to 500 msec, compared with 405 msec at baseline. Mild sinus tachycardia was reported in 2 of the other patients. In postmarketing experience, overdose with venlafaxine has occurred predominantly in combination with alcohol and/or other drugs. Electrocardiogram changes (eg, prolongation of QT interval, bundle branch block, QRS prolongation), sinus and ventricular tachycardia, bradycardia, hypotension, altered level of consciousness (ranging from somnolence to coma), rhabdomyolysis, seizures, vertigo, and death have been reported. 以上出自惠氏药厂网页 http://www.wyeth.com/products/all.asp --

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