Dr. Kun-Che Chang’s laboratory is seeking a highly motivated full-time postdoctoral associate at the Department of Ophthalmology, University of Pittsburgh. The Chang Lab studies the regulatory mechanisms of retinal differentiation and molecular mechanisms that lead to blindness, especially in glaucoma. The Chang Lab aims to utilize human stem cell and genetic therapies to treat retinal ganglion cell (RGC) loss and optic neuropathies. In particular, we use human retinal organoids to study retinal development and use rodent model to investigate axon regeneration. We further utilize single-cell RNA sequencing to analyze the molecular regulation in retinal organoid and rodent retina. Our research is aim to restore vision loss, especially caused by glaucoma and optic neuropathy. I will investigate the regulatory mechanism of RGC differentiation and apply the findings to gene and stem cell therapies. The successful postdoc will be involved in an ongoing study of stem cell and animal studies. Qualified candidates are welcome to submit a PDF file including a cover letter describing research interest, strength and previous accomplishments (1 page), CV and contacts of at least two references to Dr.Chang ([email protected]). Salary: $48,000/yr or more based on experience plus Fringe benefits including health, dental and vision insurances. Qualifications of the candidate: Ph.D. and/or M.D./Ph.D. in stem cell biology, neuroscience, developmental biology or relevant field of biomedical sciences, or M.D. of Ophthalmology. At least one first-author publication in one of the following fields: ophthalmology/vision science, developmental biology, stem cell biology. Chang lab website: https://changkc1983.wixsite.com/changlab http://ophthalmology.medicine.pitt.edu/people --

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