作者sorafenib (tomorrow will be fine)
看板Nurse
标题Re: [问题] 静脉营养
时间Thu Jul 22 13:39:42 2021
我看了几篇学术型的文章,看起来突然停用TPN并不会造成血糖过低的情形
1. Krzywda et al. JPEN J Parenter Enteral Nutr. 1993;17(1):64-67;
2. Nirula et al. Am Surg. 2000;66(9):866-869;
3. Eisenberg et al. Dis Colon Rectum. 1995;38(9):933-939)
所以後来2006年有一篇指引就表示,在停止使用TPN後发生反弹性低血糖其实很少见,
风险非常低,即便是在糖尿病族群中。
但若是真的很担心,也可以在停止前1-2小时逐渐减少输注量。
--原文如下--
(p.62)How Should PN Be Tapered?
There is a general belief that PN formulations require tapering.
Rebound hypoglycemia is rarely seen but is often discussed
in the clinical setting (59–61). The risk is very low,
even in patients with diabetes mellitus, as they are somewhat
“protected” by inherent insulin deficiency.
Stopping PN with insulin is the same as stopping an independent insulin drip;
remember, the halflife of regular insulin is only 5 minutes
(although, somewhat longer if the patient is in renal failure).
A taper down of PN is not needed, especially if the patient is receiving
another dependable source of carbohydrate.
If a particular patient is prone to hypoglycemia, tapering PN over 1–2 hours
before discontinuation is justified and can avoid this problem.
资料来源
文章标题:
The Hitchhiker’s Guide to Parenteral Nutrition Managementfor Adult Patients
https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2015/11/MadsenArticle-July-06.pdf
--我个人意见--
如果病人於注射TPN的期间所监测的血糖都在140-180mg/dl
突然停掉TPN其实身体是可以应付这样血糖的改变
并不需要太过担心
※ 引述《newpink (不是每个人都喜欢你)》之铭言:
: 先背景介绍一下,目前在中部的区域医院就职,昨日有一病人上TPN,就医院的SOP,如果
: 使用TPN的病人如果需停止或改配方为PPNNP,需使用10%葡萄糖溶液 tapping後再改,但
: 据当科VS表示,他之前在中荣受训时,可直接off,不需要10%葡萄糖,但院内营养小组不
: 同意此项作法,双方争执许久,想请问
: 1.TPN真的不需要慢慢tapping下来了吗?
: 2.如果滴注时间被延迟了,需要追量吗?
: 是否有同仁可以提供贵院做法,或者有guide line可参考?
: 付上本院TPN供参,谢谢
: https://i.imgur.com/wwPsY9u.jpg
--
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※ 编辑: sorafenib (114.34.165.248 台湾), 07/22/2021 13:45:22
※ 编辑: sorafenib (114.34.165.248 台湾), 07/22/2021 13:47:38