第二梯Intern Seminar题目 1. Which of the following statements is NOT CORRECT based on the latest epidemiologic and clinical evidence? B) A) In atopic dermatitis a mild enzyme deficiency has been proposed, resulting in altered PUFA metabolism that compromising epithelial structure and fuction. B) In asthma the hypothesis that increased omega-6 PUFA and reduced omega-3 PUFA intakes increase proinflammatory eicosanoid metabolites and PGE2-induced Th2 differentiation correlates well with the results of intervention studies. C) In atopic dermatitis the supplementation of evening primrose oil rich in omega-6 PUFA results in significant clinical improvement as well as decreases the dose of medication needed for disease control. D) In asthma omega-3 PUFA supplement may benefit some subgroup of patients, among whom decreased secretion of leukotriene C4 is observed. 2. In epidemiologic studies of this paper, beneficial associations have not been reported between Vitamins C and E, selenium, carotenoids, fruit, and C) A) asthma B) adult-onset wheeze C) coronary heart disease D) ventilatory function 3. Which one is wrong? C) A) Dietary antioxidant deficiency might influence disease pathogenesis through both immuno-modulatory and reduced antioxidant mechanism. B) Dietary antioxidant intake might be particularly important during pregnancy and early childhood. C) The results of supplementation studies have been quite satisfactory and reporting significant effects. D) Vitamin E have been reported to promote Th1 differentiation by increasing Th1 cytokine secretion and down-regulating IL-4 mRNA expression in Th cells. 4. Which of the followings about empyema is false ? D) A) Pneumococcal infection remains the most common cause in the developing world B) Staphylococcus aureus is the most common organism in developing countries C) CT scans should not be done routinely D) The mortality of children is higher than adults 5. Which of the followings about treatment of empyema is false ? D) A) Considerations should be given to treating anaerobic bacteria in children at risk from aspiration e.g. in cerebral palsy B) Surgery would result in a shorter hospital stay than chest-tube drain alone C) When loculated pockets of pus are formed , adequate drainage with a single chest drain is difficult D) Instillation of single chain urokinase plasminogen activator would cause adhesion formations 6. Which of the following is not one of the definition of ARDS? D) A) Acute onset of bilateral infiltration B) No left atrial hyptertension C) PaO2/FiO2 < 200 D) Using mechanical ventilator 7. Which of the following is not a risk factor for the mortality of ARDS? D) A) PaO2/FiO2 ratio B) Non-pulmonary and non-CNS organ failure C) CNS dysfunction D) Infection 8. 下列何者不是minimal change nephotic syndrmoe的特徵? B) A) proteinuria B) hematuria C) hypoalbuminemia D) edema 9.下列哪个基因与podocyte slit diaphragm potein 无关? D) (1) NPHS1 (2) NPHS2 (3) CD2AP (4) Ras 10. Which statement about MMf therapy is wrong? B) A) MMF dosing is similar to that used for renal transplantation B) MMF therapy should be maintained for 3 months C) Disease duration and patient age at the start of the MMF protocol are not factors influencing the response to MMF. D) MMF has fewer undesirable effects and an efficacy at least equivalent to CsA in cases of steroid dependence 11. To compare the relative risk of relapses, which C0-MPA level do we use a cut-point? C) A) 1.5 B) 2.0 C) 2.5 D) 3.0 共11题 --

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