课程名称︰遗传学 课程性质︰必修 课程教师︰陈凯仪 开课学院：生农学院 开课系所︰农艺系 考试日期（年月日）︰99/6/23 考试时限（分钟）：110分钟 是否需发放奖励金：是 （如未明确表示，则不予发放） 试题 : 1.选择题(60分；每题3分) (1)Which is the correct order of stages in the cell cycle? a.G1, S, prophase, metaphase, anaphase. b.S, G1, prophase, metaphase, anaphase. c.prophase, S, G1, metaphase, anaphase. d.S, G1, anaphase, prophase, metaphase. (2)Which of following events takes place in meiosis II but not in meiosis I? a.Crossing over. b.Contraction of chromosomes. c.Separation of homologous chromosomes. d.Separation of chromatids. (3)What was the genotype of the few F1 red-eyed males obtained by Bridges when he crossed a white-eyed female with a red-eyed male? a.X+. b.XwX+Y. c.X+Y. d.X+X+Y. 注:绿色部份为上标,以下皆为同样意义 (4)A male affected with an X-linked dominant trait wil have what proportion of offspring affected with the trait? a.1/2 sons and 1/2 daughter. b.All daughters and no sons. c.All sons and no daughters. d.3/4 daughters and 1/4 sons. (5)For single crossovers, the frequency of recombinant gametes is half the frequency of crossing over because a.A testcross between a homozygote and heterozygote produces 1/2 heterozygous and 1/2 homozygous progeny. b.The frequency of recombination is always 50%. c.Each crossover takes place between only two of four chromatids of a homologous pair. d.Crossover occur in about 50% of meiosis. (6)Which process of DNA transfer in bacteria requires a virus? a.Conjugation. b.Transduction. c.Transformation. d.All of the above. (7)Conjugation between an F+ and an F- cell usually results in a.Two F+ cells. b.Two F- cells. c.An F+ and an F- cell. d.An Hfr cell and an F+ cell. (8)In complementation tests, Benzer simultaneously infected E. coli cells with two phages, each of which carried a different mutation. What conclusion did he make when the progeny phage produced normal plaques? a.The mutations occured at the same locus. b.The mutations occured at different loci. c.The mutations occured close together on the chromosome. d.The genes were in the cis-configuration. (9)A dicentric chromosome is produced when crossing over takes place in an individual heterozygous for which type of chromosome rearrangement? a.Duplication. b.Deletion. c.Paracentric inversion. d.Pericentric inversion. (10)Species A has 2n=16 chromosomes and species B has 2n=14. How many chromosomes would be found in an allotriploid of these two speceis? a.21 or 24. b.42 or 48. c.22 or 23. d.45 (11)How do the sugars of RNA and DNA differ? a.RNA has a six-carbon sugar; DNA has five-carbon sugar. b.The sugar of RNA has a hydroxyl group that is not found in the sugar of DNA. c.RNA contains uracil; DNA contains thymine. d.DNA's sugar has a phosphorous atom; RNA's sugar does not. (12)What is tertiary level of DNA structure? a.Structure of the nucleotides. b.How the nucleotides are joined together. c.Three-dimensional structure of the double helix. d.Higher order folding of DNA. (13)Most of the genes that encode proteins are found in a.Unique-sequence DNA. b.Moderately repetitive DNA. c.Highly repetitive DNA. d.All of the above. (14)Discontinuous replication is a result of which property of DNA? a.Complementary. b.Charges phosphate group. c.Anti-parallel nucleotide strands. d.Five-carbon sugar. (15)Which class of RNA is correctly paired with its function? a.Small nuclear RNA (snRNA): prcesses rRNA. b.Transfer RNA (tRNA): attaches to an amino acid. c.Micro RNA (miRNA): carries information for the amono acid sequence of a protein. d.Ribosomal RNA (rRNA): carries out RNA interference. (16)If a splice site wre mutated so that splicing did not take place, what would the effect be on the protein encoded by the mRNA? a.It would be shorter than normal. b.It would be longer than normal. c.It would be the same length but would have different amino acids. (17)A codon is a.One of three nucleotides that encodes an amino acid. b.Three nucleotides that encode an amino acid. c.Three amino acids that encodes a nucleotide. d.One of four bases in DNA. (18)Which of the following changes is a transition base substitution? a.Adenine is replaced by thymine. b.Cytosine is replaced by adenine. c.Guanine is replaced by adenine. d.Three nucleotide pairs are inserted into DNA. (19)What statement is not an assumption of the Hardy-Weinberg law? a.The allelic frequencies (p and q) are equal. b.The population is randomly mating. c.The population is large. d.Natural selection has no effect. (20)If the environmental variance (I/E) increases and all other variance components remain the same, What will the effect be? a.Broad-sense heritability will decrease. b.Broad-sense heritability will increase. c.Narrow-sense heritablility will increase. d.Broad-sense heritability wil increase, but narrow-sense heritability will decrease. 2.问答题(24分; 第1、2题各6分, 第3题12分) (1)How do complete dominance, incomplete dominance, and co-dominance differ? (2)How might you determine whether a particular trait is due to cytoplasmic inheritance or to genetic maternal effect? (3)Please write down the names of the six mutant types in Muller's classification(based on the degree of severe phenotypes) and the possible gene action(dominance or recessive) for each type of mutant alleles. 3.计算题(16分, 第1、2题各4分, 第3题8分) (1)Assume that long ear lobes in humans are an autosomal dominant trait that exhibit 30% penetrance. A person who is heterozygous for long ear lobes mates with a person who is homozygous for normal ear lobes. What is the probability that their first child will have long ear lobes? (2)In an experimental population of flour beetles, the body length shows a continuous distribution with a mean of 6 mm. Agroup of males and females with body length of 9 mm are selected and interbred. The body length of their offspring average 7.2 mm. Please calculate the realized heritability for body length in this population. (3)In Antirrhinum plants, two pure-breeding white-flowered lines are intercrossed, and all F1 progenies are white-flowered plants. By self-pollinating an F1 progeny, 131 F2 progenies are white-flowered plants, while 29 F2 progenies are red-flowered plants. A)Deduce the genotypes of these phenotypes(including two parental lines, F1 and F2 progenies), using clearly defined gene symbols. B)Predict the outcome of crosses of the F1 to each parental line. --

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