课程名称︰神经生物学 课程性质︰群组必修 课程教师︰杨恩诚 开课学院：生农学院 开课系所︰昆虫系 考试日期（年月日）︰99.4.19 考试时限（分钟）：3hr 是否需发放奖励金：是 （如未明确表示，则不予发放） 试题 : 1.What are the different levels of analysis in neuroscience research? What types of question do researchers ask at each level? Please give 10 types of them. 2.Colchicine is a drug that causes microtubules to break apart (depolymerize) What effect would this drug have on anterograde transport? What would happen in the axon terminal? 3.When the brain is deprived of oxygen, thh mitochondria whithin neurons cease producing ATP. WHat effect would this have on the membrane potential? Why? 4.What ions carry the early inward and late outward currents during the action potential? 5.Define membrane potential (Vm) and sodium equilibrium potential (E Na). Which of these, if any, changes during the course of an action potential? 6.Why is an excitatory synapse on the soma more effective in evoking action potentials in the postsynaptic neuron than an excitatory synapse on the tip of a dendrite? 7.List the criteria that are used to determine whether a chemical serves as a neurotransmitter. What are the varioius experimental stratehies you could use to show that ACh fulfills the criteria of a neurotransmitter at the neuromuscular junction? 8.The transduction of saltiness is accomplished, in party, by a Na+ -permeable channel. Why would a sugar permeable membrane channel be a poor mechanism for the transduction of sweetness? 9.How does the membrane potential change in response to a spot of light in the receptive field center of a photoreceptor? Of an On bipolar cell? Of an OFF- center ganglion cell? Why? 10.List the chain of connections that link a cone in the retina to a blob cell in striate cortex. 11.How do you localoze the sound in the horizontal plane and in the vertical plane? --

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