课程名称︰生物化学甲下 课程性质︰必修 课程教师︰张震东教授 开课学院：生物资源暨农学院 开课系所︰生物化学研究所 考试日期（年月日）︰不明 考试时限（分钟）：120分钟 是否需发放奖励金：是 （如未明确表示，则不予发放） 试题 : 1. What are the advantages of using triacylglycerols as stored fuels? (5%) 2. What are the five general types of membrane lipids? (5%) 3. Please explain why glycerol is prochiral. (5%) 4. Please give the structure of phosphotidylinositol 4,5-bisphophate (5%) and the sites of action by phospholipase A1, A2, C and D. (5%) 5. Please describe the asymmetric distribution of phospholipids between the inner (cytoplasmic) and outer (extracellular or exoplasmic) monolayers of the erythrocyte plasma membrane. (5%) 6. Please describe peripheral and integral proteins. (5%) 7. What are hydropathy curve and its application? (5%) 8. Please describe the structural features and possible functions of lipid rafts. (10%) 9. Please describe the cellular pathway leading to increased glucose uptake in skeletal muscle after meal. (5%) 10. Describe how V-type ATPases are important for the infection of the influenza virus? (10%) 11. Please distinguish carriers and channels. (5%) 12. Discuss why ketone bodies are excessively form in untreated diabetes. (10%) 13. Describe the mode of action by the following drugs; Celecoxib and Rosiglitazone. (10%) 14. Describe the two general strategies for forming the phosphodiester bond of phospholipids. (5%) 15. Describe how synthesis of cholesterol is regulated. (10%) 16. Describe the reverse cholesterol transport by HDL. (10%) --

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