交通大学、清华大学 统计学研究所 专题演讲 题　目：Using Comparative Genomics to Predict Disease-Relevant Genes 主讲人：Dr. Juan Antonio Gabaldon Estevan Centre for Genomic Regulation (Barcelona, Spain) 时　间：98年8月18日(星期二)下午15:00-15:50 (下午14:40-15:00茶会於交大统计所429室举行) 地　点：交大综合一馆427室 Abstract The era of genomics has opened new possibilities for the computational prediction of protein function. In particular, the comparison of fully sequenced genomes allows us to investigate the so-called genomic context of a gene, which includes its chromosomal positioning relative to other genes as well as its evolutionary record among the genomes considered. This information can be exploited to find functionally interacting partners for a protein of unknown function and thus obtain information on the biological process in which it is playing a role. I will highlight some examples from our own research which include the finding of novel genes involved in mitochondrial dysfunction and the search for novel virulence pathways in pathogenic fungi. 务 必 参 加 --

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