题　目：An Extended Ancestral Mixture Model for Phylogenetic Inference under the HKY DNA Substitution Model 主讲人：Prof. Shu-Chuan Chen (Idaho State University, USA ) 时　间：102年1月8日(星期二)下午15:30-16:20 地　点：交大综合一馆427室 Abstract Inferring phylogenies is important in many scientific areas such as biology, paleontology, biochemistry and bioinformatics. Many statistical methods have been proposed to reconstruct the phylogeny from the DNA sequences, such as Maximum Parsimony method, Distance method, Maximum Likelihood method and Bayesian method. Recently, a new method, Mixture Ancestral Models has been proposed by Chen and Lindsay (2006) to infer phylogeny from the binary DNA sequences. In the talk, we extend the ancestral mixture models to the one which can infer phylogeny from the DNA sequences with multiple states. By varying the time parameter, one can create a hierarchical tree that estimates the population structure at each fixed backward point in time. Theoretical and computational properties and applications of the extended ancestral mixture model will be presented. --

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