作者aaaw (alal)
看板LifeSci_Work
标题[情报] "为什麽DNA比RNA稳定?" 的答案
时间Tue Oct 5 22:03:57 2004
主要就是因为DNA没有2' OH基, 所以不会攻击磷酯键,
造成裂解(auto-catalytic cleavage),RNA则相反,故DNA较稳定.
原文整理:
The chemical difference between RNA and DNA (without 2’ hydroxyl group) makes
DNA a good permanent information storage molecule, while RNA is used for
temporary information storage.
Because ribose has both 2’ and 3’ hydroxyl groups, the 2’ hydroxyl group can
attack the phosphodiester bond in the presence of hydroxyl radicals, which
results in the phosphate backbone being broken. This reaction can occur
spontaneously at neutral pH and is called auto-catalytic cleavage.
Because DNA does not have a 2’ hydroxyl group, DNA molecules cannot undergo
auto-catalytic cleavage, and are therefore much more stable than RNA.
原本找到的网址没有记下来, 不过大概就是这样了.
祝大家考试顺利!
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