承昌、怡静、小学生、我、湘涵、78、士奇 函芩、BOSS、孟谦、家宁、芷绮、燕如 请看过来唷~ 讨论一下CS吧 (恩 因为没人po所以...) 讨论时间定在下周三78节 地点借到再通知 因为不知如何分配题目~所以就照学号来吧! ex.78是第6题 以此类推~ 到时请大家做好讲稿和PPT唷 看完请推个文吧<(￣︶￣)@m 以下是题目 (原文请大家上学习平台) Q1: What vital signs or symptoms do Patient A and Patient B have? Q2: What neuron in the CNS controls skeletal muscle contraction? Is this kind of neurons' activities also controlled by interneurons? Q3. Please draw the contractile structure of the skeletal muscles and draw a neuromuscular junction (NMJ). Q4. What neurotransmitter is used at the N-M junction? How is the neurotransmitter released and recycled? And how does that release excite skeletal muscle contraction? Q5: What is end-plate potential? Q6. Please describe the excitation-contraction coupling events (including the cross-bridge cycle) in the skeletal muscles and how Ca++ ions are involved. Q7: From questions 2 and 6, please list the possible sites along the activation of the motor neuron axon to the contraction of muscles, and describe defects in which step(s) might cause muscle contraction problems? Q8. What is tetanus infection? How would the tetanus infection cause Patient A's spastic contraction? What is myasthenia gravis (MG)? How would MG cause Patient B's muscle weakness? Q9: How could decline in muscle function (muscle weakness) contribute to the eye and visual problems and chewing problems of Patient B? Why is neostigmine used as the treatment for Patient B? Q10: Are there any ways to confirm that patient B's muscle weakness is not due to nerve conduction problem or defects in muscle itself? Q11: What are single fiber electromyography (SFEMG), repeated nerve stimulation (RNS), chest CT scan, tensilon test and serum test? Why are the physiological significances in using these tests for myasthenia gravis diagnosis? Does Patient A need to so those tests? Q12: Have you ever heard of Lambert-Eaton myasthenic syndrome (LEMS)? Is there any test that you can do to differentiate myasthenia gravis from Lambert-Eaton syndrome? Q13: One way to treat MG is to remove the thymus. Why? --

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