※ 引述《over999 (唉呦)》之铭言： : 请问我想找关於基因表现出的蛋白 : 在细胞中的位置 除了GeneCards和 Human protein Atlas之外 有更好的网站有标出Sub-c : ellular localization吗 : 谢谢! : BTW 我还想问 : Metacore/IPA等大资料库中的Subcellular 是准的吗 有些基因在网站跟软体中写的位置 : 不太一样欸 Gene ontology db 用过吗? Ontologies Cellular Component These terms describe a component of a cell that is part of a larger object, such as an anatomical structure (e.g. rough endoplasmic reticulum or nucleus) or a gene product group (e.g. ribosome, proteasome or a protein dimer) 定义精细到我很难用 例如底下这个 分类超级细 Name transmembrane transporter complex Definition A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. http://imgur.com/a/rirAg 从上图看得出来 除了transmembrane transporter complex还有其他比较粗的分类 你可以当作大分类及小分类的概念 做高通量分析使用小分类会搞死自己，而用大分类又骚不到痒处 至於证据 资料库也有标示 证据程度由大到小 direct assay evidence used in manual assertion sequence similarity evidence used in manual assertion biological aspect of ancestor evidence used in manual assertion curator inference used in manual assertion physical interaction evidence used in manual assertion genetic interaction evidence used in manual assertion IPA等资料库基本上都会参考这个资料库的内容 因为这个资料库一来免费 二来公开检视资料 应该对你有帮助 Jack --

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