CE is less reactive, therefore it is natural for cells to store their cholesterol in the esterified form (mainly in the lipid droplet). Free Cholesterol is prone to oxidation and peroxidation, which are essentially toxic to the cells. On top of that, oxysterols are also important regulators in many pathways, so it is likely for cells to prevent unecessary oxysterol formation. These are probably considered to be the main reasons for the esterification of cholesterol. To support that, recent study also showed that accumulation of free cholesterol will lead to apoptosis. Sorry about the English, but I don't think I can explain it as well in Chinese. There are too many "terms" that I do not know in Chinese. Hope this will help. ※ 引述《hosaka (爱情很难)》之铭言： : 【问题】：为什麽胆固醇要再酯化成CE? : 【问题起因】：不了解酯化成CE的原因 : 【个人看法】：有什麽差别吗??不了解 --

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