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标 题Re: Promoter SNPs
发信站GRNET, Greece (Thu Oct 5 15:49:33 2006)
转信站ptt!ctu-reader!ctu-peer!news.nctu!newshub.sdsu.edu!newsfeed.freenet.de
On Thu, 05 Oct 2006 07:42:37 +0300, VP <
[email protected]>
wrote:
1) How about this method:
I went here: www.pubmed.com and I have chosen the GENE database.
Let's say I was interested at the VWF promoter gene polymorphisms.
I typed VWF itno the search box and it gave me the VWF gene
information for several organisms. I chose HOMO SAPIENS, but not the
gene itself but the word links at the top right of the name of the
gene.
Then I chose GeneViewIndbSNP and it gave me all the SNPs for the VWF
gene, here:
http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=7450.
At the bottom of this page there are 11 SNPs, TO THE GENOMIC REGION
NEAR THE VWF GENE. My question is:
ARE THESE SNPs PROMOTER SNPs?
2) I have also found this:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1361283
Is it worth trying? I tried it and it gave me a dead link.
3) Another question: If you have the RS number for a given SNP, is
there an easy way to find if this is a promoter SNP?
>>Here is the thing:
>>
>>I search here
>>
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp
>>
>>for SNPs that concern the promoter of several genes.
>>
>>My question is:
>>
>>1) Am I searching iat the right place, or should I try here:
>>
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed ?
>>
>>2) If this is the right place
>>(
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp)
>>
>>which option should I use from the "limits" section in order to take
>>as results only the "promoter SNPs"?
>>
>>3) If this is not the right place
>>(
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp)
>>
>>where and under which keywords or limits should I search?
>>
>>Thanks in advance