中文文字部分来自 以色列经济贸易办事处 http://itrade.gov.il/taiwan/?p=4332 文字内容出处 八仙尘爆後，许多人因此而留下无法抹灭的痕迹，虽然存活了下来，但这些永久存在的疤 痕也许会造成生理、心理甚至是社交上的压力。以色列特拉维夫大学以及美国哈佛大学的 顶尖研究员共同致力於烧烫伤复原的领域，发展了一项不需要额外手术的方式让伤口自然 的复原，并不留下疤痕的技术。 遭受烧烫伤後，过多的胶原蛋白的产生是导致疤痕留下的原因。而研究团队所发展的特殊 技术partial irreversible electroporation (pIRE)，是能够防止烧烫伤疤痕形成的关 键。在一连串的老鼠实验後，与未治疗的对照组相比，经过六个月治疗的疤痕区域很明显 有57.9%的减少，研究团队也正努力找出治疗技术的平衡点，避免过度治疗或是形成新的 伤口。现在，他们找到了开关，而下一步，将会是募资并执行进一步的人体临床试验，相 信未来此技术将会在医界里注入新的能量。 英文资料出处 http://goo.gl/HKP9Qu AUGUST 15, 2016, 8:20 AM 相关资料下载 http://goo.gl/gI1SMf Novel non-invasive technology may prevent burn scars Israeli and American researchers develop method to control collagen-cell proliferation that produces scarring. A group of researchers from Tel Aviv University and Harvard University is proposing a new non-invasive method to prevent burn-related hypertrophic scars — raised tissue caused by excessive collagen — using short, pulsed electric fields. “People don’t die from scars, but they do suffer from them,” said Dr. Alexander Golberg of TAU’s Porter School of Environmental Studies. “We believe that the technology we developed, called partial irreversible electroporation (pIRE), can be used to prevent debilitating burn scars from forming.” According to the World Health Organization, 10 percent of all unintentional-injury deaths result from burns. But even for those who survive the destruction of skin and tissue cells, post-burn scarring creates lifelong physical, psychological and social suffering. The experimental pIRE technique harnesses microsecond-pulsed, high-voltage, non-thermal electric fields to control the body’s natural response to trauma — the proliferation of collagen cells that cause permanent scarring at the site of injury. The technique was applied to burn injuries in rats during five therapy sessions over the course of six months. Using an imaging technique developed at the Wellman Center of Photomedicine at Massachusetts General Hospital, the researchers assessed the treated wounds and found a 57.9% reduction of the scar area in comparison with untreated scars. The researchers tried to find a delicate balance so that the technique didn’ t create a new wound or “overheal” the existing wound, because scarring is the body’s natural way of healing. The study, supported by the Shriners Foundation, was led by Golberg together with Dr. Martin Yarmush of the Center for Engineering in Medicine at Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital in Boston. Researchers from Harvard-affiliated institutions and from the department of biomedical engineering at the University of Arkansas also participated. Their results recently were published in the Journal of Investigative Dermatology. The authors caution that the findings were limited by the fact that rats do not develop hypertrophic scars and therefore human trials are essential. “Scarring is a very complex process, involving inflammation and metabolism, ” said Golberg. “We have found a way to partially prevent scar formation in animal models. Next we need to raise funding to develop a device for the clinical study on humans.” Surgical excision, laser therapy, electron-beam irradiation, mechanical compression dressing, silicone sheet application and other techniques have been tested to treat scars over the years, said Golberg. “But there have been only modest improvements in the healing outcomes among all these treatments.” --

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