After reading the paper(J. Org. Chem. 2004, 69, 2917-2919), I was much touched by the following paragraphs. May this also encourge all of us. "I believe even more strongly that the 21st century will see the general availability of up-to-date, good-quality basic health care and education in all countries of the earth beca use this will be seen by the more advanced countries not only as achievable but also as a prerequisite to world stability and the well being of peoples everywhere. I hope that it is not an impossible dream because the economic and social benefits will be great, especially as medicine advances. I believe that scientists, medical professionals, economists, the media, those skilled in governance, and especially the young and altruistic should start to champion this cause and make clear plans for how it might be accomplished. I should stress the young because it will be a very complex and lengthy undertaking. To them and to those starting careers in chemistry, I would offer the following advice: Never underestimate what you can accomplish if you prepare yourself well, continue to learn, work hard and optimistically, and value your integrity. I am often asked about my vision for the future of chemistry, especially synthetic chemistry. As just stated, I believe that chemical synthesis will make enormous contributions to human progress in the next century especially when coupled to biology and medicine. However, those developments will not be fully realized without great and continuing advances in the central disciplines of chemistry. There is so much that remains to be discovered, in my opinion, that today's chemistry will seem archaic to a 22nd century chemist. I envy the young people in chemistry who will experience the excitement and pleasure of making the many discoveries of the next century of chemical research. Yet, at the same time, I worry about whether the younger generations of this country and the world will aspire to high creativity and persevere to achieve their impossible dreams. --

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