作者stacyyh (消失的射手座)
看板Anti-Cancer
标题左侧液下肿瘤报告
时间Thu Oct 26 14:20:02 2023
不好意思，因要好几项报告，还是下面的才是切片报告?
9/25 免疫组织化学染色(每一抗体)
Lymph node, axillary, left, core needle biopsy, carcinoma, metastatic.Description:The specimen submitted consists of 5 tissue fragments measuring up to 1.2x0.1x0.1 cm in size, fixed in formalin. Grossly, they are whitish and soft. All for section after bisection and labeled as A1-A2; Jar: 0 An/SMicroscopically, sections reveal metastatic carcinoma arranged in sheets or nests with desmoplasia in the lymphoid background. Moderately nuclear atypism is found. Marked mitotic figure is noted. The tumor cells
show TRPS1(+) by immunostain. Breast origin is favored.
IMMUNOHISTOCHEMICAL STUDY The tissue was fixed in 10% neutral buffered formalin. The fixation time of the tissue was longer than 6 hours and shorter than 72 hours.Cold Ischemia Times was less than 1 hour: Yes.Testing platform: Ventana BenchMark Series, Detection system: Ventana Ultraview DAB IHC Detection kitDESCRIPTION1. ESTROGEN RECEPTOR by VENTANA (clone: SP1) monoclonal rabbit anti-human estrogen receptor antibody: negative nuclear staining in invasive tumor cells(Internal control: absent)”No
internal controls are present, but external controls are appropriately positive. If needed, testing another specimen that contains internal controls may be warranted for confirmation of ER status.”2. PROGESTERONE RECEPTOR by VENTANA (clone: 1E2) monoclonal rabbit anti-human progesterone receptor antibody: negative nuclear staining in invasive tumor cells.(Internal control: absent)3. HER2/neu by Ventana (clone: 4B5) rabbit monoclonal anti-human c-erbB2 oncoprotein antibody: negative membrane staining in
invasive tumor cells 4. Ki-67 by Cell Marque (clone: SP6) monoclonal antibody: Percentage of positive nuclei: 45 %INTERPRETATION1. ESTROGEN RECEPTOR: negative (＜1 %).2. PROGESTERONE RECEPTOR: Negative (＜1 %).3. HER2/neu: according to ASCO/CAP Guideline Update (J Clin Oncol. 2018 Jul 10;36(20):2105-2122. The HER2/neu overexpression assessment is Negative (score 0): No staining is observed or Membrane staining that is incomplete and is faint/barely perceptible and within ≦10% of tumor cells.”This test
was developed and its performance characteristics determined by the Department of Surgical Pathology of Changhua Christian Hospital. It has been approved by the U.S. Food and Drug Administration.”This assay has not been validated on decalcified tissues. Results should be interpreted with caution given the likelihood of false negativity on decalcified specimens.4. Ki-67 proliferation index (45%)The pathologic diagnosis has been discussed and confirmed by Peer Slide Review.Dr.Wei-Hsiang Chang
Ref:K12141519, K12147007, K22126959
婆婆(68岁)左侧液下就医检查为2cm左右肿瘤，
切片後医生说是恶性，
目前排乳房、胸腔断层、大肠镜、腹部超音波都没有发现癌症转移
医生说治疗要连左边乳房一起切除，并要接受化疗，原本这周三或周五就可以动刀，因考虑
有预约斗六台大下周二外科门诊想做确认，或是否有其他治疗方式?
9/28 切片报告
Indication : Other : LT AXILLARY LYMPHADENOPATHY FOR CNB 左侧 最大径 18.15 X 12.
10/7 乳房造影术
1. Indication for examination:= Diagnostic mammogram RCC RMLO LCC LMLO2. Glandul
Tissue diagnosis Note: The false-negative rate of mammography is approximately l
看版友说要看分类,
但怎麽9/28的说是4A? 10/7里面却是4C?
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1F：推 Euglena: 可以多找几位乳房外科医师谘询 10/26 21:30
2F：→ stacyyh: 谢谢你!我再想是不是可以做核磁共振之类更详细的检查? 10/27 06:54
3F：推 frgthy: 病理没有看到恶性的描述 10/27 23:37
4F：→ frgthy: 4A/C是影像学的怀疑，确认需要病理 10/27 23:39
5F：→ frgthy: 应该说上面是超音波，底下是乳房摄影报告，没有看到切片 10/27 23:40
6F：→ frgthy: 结果 10/27 23:40
※ 编辑: stacyyh (1.170.132.57 台湾), 10/28/2023 12:50:10
7F：推 dolo: 楼上说错了，第一行Lymph node, axillary, left, core need 10/28 18:24
8F：→ dolo: le biopsy, carcinoma, metastatic.就已经说切片是恶性的了 10/28 18:24
9F：→ dolo: ，里面叙述有写favor breast origin，就是说认为是乳癌 10/28 18:24
10F：→ stacyyh: 谢谢你，楼上看的是我先前贴的报告，没有第一段报告内容( 10/28 19:32
11F：→ stacyyh: 今天才修正贴文) 10/28 19:32
12F：推 dolo: 谢谢原po说明 误会f大了 10/28 21:56
13F：→ kingsupercat: 以目前的情况来看应该还是手术为优先，至於考虑到其 11/02 09:41
14F：→ kingsupercat: 它的疗法，可以考虑免疫细胞治疗。 11/02 09:42