※ 引述《prehn (dicey and paltry)》之铭言： : ※ 引述《winibaby (winibaby的冒险)》之铭言： : : 不好意思 我想请问一下 : : 因为他听说可以治疗 肺癌 : : 希望有人可以解惑谢谢 : : 而且吃他的副作用有可能有间质性肺炎 : : 是什麽情形呢？？ : 只能用在非肺小细胞癌罗... : 最好有EGFR MUTATION, EXON 16,17,18 吧... 还要在後面壹点 exon 18, 19, 20, 21 卓参 详见 paper from CGMH VGH-TPE Mutation in the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor Is a Predictive and Prognostic Factor for Gefitinib Treatment in Patients with Non–Small Cell Lung Cancer Clin. Cancer Res. 2005 11: 3750-3757. High Frequency of Epidermal Growth Factor Receptor Mutations with Complex Patterns in Non–Small Cell Lung Cancers Related to Gefitinib Responsiveness in Taiwan Clin. Cancer Res. 2004 10: 8195-8203. sorry 我打字 慢 to put it in English exon 18, 19, 20, 21 are the tyrosin kinase domain untill exon 21 Pao W, Miller V, Zakowski M, Doherty J, Politi K, et al. (2004) EGF receptor gene mutations are common in lung cancers from “ never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101: 13306–13311 : 效果一到二成..... : 但我有看过效果不错的...吃二个多月. 肿瘤全消... : 但他的EGFR MUTATION 好像有 PRESENT : TARCEVA 也是新一代的罗... irresa seems to be ALMOST withdrawal or LIMITED in its indication as FDA announced (IRRESA withdraw its application in European market) http://www.fda.gov/cder/drug/infopage/iressa/iressaQ&A2005.htm Date created: June 17, 2005 (this is due to the fact that the end point of trial IDEAL or what ?(ISEL) showed no advantage, comparing irresa and placebo) TARCEVA now turn to "the only" FDA approved EGFR-TKI Are TARCEVA related to anti-angiogenesis ? : EGFR-TKI : 知道就这些啦.... : m34789 --

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