代po 手机排版请见谅 Title] Postdoctoral Fellows [Job Location] University of Texas Health Science Center at Houston McGovern Medical School Department of Integrative Biology and Pharmacology Dr. Dung-Fang Lee Laboratory [Description] Modeling human genetic disease has recently become feasible with induced pluri potent stem cell (iPSC) methodologies. iPSCs provide a powerful and unlimited source of cells to generate differentiated cells that can be used to elucidate disease pathogenesis, for drug discovery and development, toxicology screenin g, personalized healthcare and eventually cell transplantation-based therapies . Our laboratory is dedicated to understanding cancer pathological mechanisms by applying patient-specific iPSCs and/or engineered ESCs. We particularly foc us on cancer-prone genetic disease disorders including Li-Fraumeni syndrome (L FS) and hereditary retinoblastoma. We apply systems biology approaches to diss ect cancer etiology and plan to develop potential therapeutic strategies to tr eat and prevent cancers. [Job Start Time] 2021 August (negotiable) [Lab website] https://www.dfleelab.org/ https://med.uth.edu/ibp/faculty/dung-fang-lee-phd/ [Job Qualifications] Qualified candidates should have a Ph.D. in stem cell, genetics, animal models , cancers, or other related fields. Expertise in iPSC and tissue culture, func tional characterization of transcription factors, experience in next generatio n sequencing analysis, and interests in iPSC-based disease platform and bone c ancer preferred. If you are interested in iPSC-based cancer research and our research topics, p lease send your CV and a brief description of research interests to Dr. Dung-F ang Lee (email: [email protected],edu) --

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