Postdoctoral position in Cryo-EM at the University of Colorado Denver A postdoctoral position in cryo-electron microscopy (cryo-EM) is available in the Asturias laboratory at the University of Colorado Anschutz Medical School (Denver CO). The Asturias group has considerable expertise in cryo-EM studies of transcription and chromatin regulation, and has made important contribution in these and other areas (e.g., Tsai, et al. 2014 Cell 157:1430; Tsai, et al. 2017 Nature 544:196; Brignole, et al. 2018 eLife, pii: e31502. doi: 10.7554/e Life.31502). The Anschutz Medial School is home to a large number of outstandi ng research groups and offers an extraordinary level of collegiality and an su perb training environment. Several new projects of direct human health relevan ce offer great opportunities for postdoctoral researchers interested in learni ng and applying cutting-edge cryo-EM. The Anschutz Medical School has a state-of-the-art cryo-EM facility equipped w ith a 200kV Arctica X-FEG electron microscope outfitted with an Autoloader, a Gatan K3 direct electron detector and a Volta Phase Plate. A new Talos L120C s creening microscope and all ancillary equipment required for the most current cryo-EM work are also available. The facility, administered by a full-time man ager, is set up for automated data collection and on-the-fly image pre-process ing, and counts with professionally-supported computational resources. The Uni versity of Colorado Boulder campus (30 miles from Denver) offers access to a 3 00kV Titan microscope equipped with a Gatan K2 direct electron detector. Denve r is consistently ranked as one of the most desirable places to live in the US , providing a fantastic environment and extraordinary opportunities for cultur al and outdoor activities. Candidates with a background in cryo-EM, X-ray crystallography, transcription or chromatin regulation are especially encouraged to apply, but motivated and well-qualified candidates will other experience will be considered. The succes sful candidate will be compensated according to current NIH guidelines and wil l be supported by grant and departmental funds for a period of at least 2 year s. If interested, please email your CV and contact information for three referenc es to: Francisco Asturias [email protected] --

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